BV421-B*41:03/Human HNRNPC (AEMYGSVTEHPSPSPL) MHC Tetramer
CAT#: MHC-LC1582
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of HNRNPC-derived peptide of AEMYGSVTEHPSPSPL covering 102-117 and B*41:03 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5223/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/75755/1894_G2_3_selected.jpg
Normal Tissue
Figure 3 IHC staining of human prostate
Immunohistochemical staining of human prostate shows strong nuclear positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5223/ihc_selected.jpg
Normal Tissue
Figure 4 IHC staining of human tonsil
Immunohistochemical staining of human tonsil shows strong nuclear positivity in germinal center cells and non-germinal center cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/75755/159385_A_5_8_selected.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Nuclear Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5223/13358_A_9_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5223/13358_A_9_5.jpg
Normal Tissue
Figure 7 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Peritubular cells Staining: Medium Intensity: Moderate Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/51075/124984_A_6_6.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/51075/124984_A_7_8.jpg
Normal Tissue
Figure 9 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/51075/124984_A_9_3.jpg
RNA Expression
Figure 10 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000092199-HNRNPC
❮
❯
Specifications
- Allele
- B*41:03
- Class
- Class I
- MHC Species
- Human
- Antigen
- HNRNPC
- Antigen Species
- Human
- Peptide
- AEMYGSVTEHPSPSPL
- Range
- 102-117
- Conjugate
- BV421
- Application
- FCM
Target
- Antigen Introduction
- This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene.
- Alternative Names
- HNRNPC; heterogeneous nuclear ribonucleoprotein C (C1/C2); C1; C2; HNRNP; HNRPC; SNRPC
- Gene ID
- 3183
- UniProt ID
- P07910
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MSDS
COA
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Lot Number:
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|---|---|---|---|
| MOB-0611CT | Recombinant Mouse anti-Human HNRNPC Monoclonal antibody (5G5) | ELISA, ICC, IF, IHC-P, IP, WB | |
| MRO-0760-CN | Rabbit Anti-HNRNPC Recombinant Antibody (clone CBACN-281) | WB, IF, IHC, IP, FC | Rabbit IgG |
| ZG-0741J | Rabbit Anti-HNRNPC Recombinant Antibody (clone 9G1) | ELISA, WB, IHC, IF, FC, IP | Rabbit IgG |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1580 | PE-B*41:03/Human HNRNPC (AEMYGSVTEHPSPSPL) MHC Tetramer | FCM | |
| MHC-LC1581 | APC-B*41:03/Human HNRNPC (AEMYGSVTEHPSPSPL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1646 | Rabbit Anti-HNRNPC Recombinant Antibody (clone DS1646AB) | WB, IHC-P, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1112 | AbPlus™ Anti-HNRNPC Magnetic Beads (VS-0724-YC1112) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1043 | Anti-HNRNPC Immunohistochemistry Kit | IHC | |
| VS-0525-XY3235 | Anti-Mouse HNRNPC Immunohistochemistry Kit | IHC | |
| VS-0525-XY3234 | Anti-Human HNRNPC Immunohistochemistry Kit | IHC |
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