Recombinant Anti-CD19 × Anti-CD28 Bispecific Antibody (Fab2)

CAT#: FAB-L059

Recombinant Anti-CD19 × Anti-CD28 Bispecific Antibody (Fab2) is composed of the Fab of the anti-CD19 monoclonal antibody and Fab of an antibody specific for CD28. A linker is added between the two Fab. This BsAb can retarget of T cells to tumor cells. It was designed for the treatment of chronic lymphocytic leukemia and follicular lymphoma.

Specifications

  • Target
  • CD19 & CD28
  • Type
  • Fab2
  • Species Reactivity
  • Human
  • Target 1
  • CD19
  • Host Species 1
  • Mouse
  • Target 2
  • CD28
  • Host Species 2
  • Mouse
  • Related Disease
  • Chronic lymphocytic leukemia and Follicular lymphoma.

Target

  • Target 1
  • CD19
  • Alternative Names
  • CD19; CD19 molecule; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4
  • Target 2
  • CD28
  • Alternative Names
  • CD28; CD28 molecule; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
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