Recombinant Anti-CD19 × Anti-CD28 Bispecific Antibody (Fab2)
CAT#: FAB-L059
Recombinant Anti-CD19 × Anti-CD28 Bispecific Antibody (Fab2) is composed of the Fab of the anti-CD19 monoclonal antibody and Fab of an antibody specific for CD28. A linker is added between the two Fab. This BsAb can retarget of T cells to tumor cells. It was designed for the treatment of chronic lymphocytic leukemia and follicular lymphoma.
Specifications
- Target
- CD19 & CD28
- Type
- Fab2
- Species Reactivity
- Human
- Target 1
- CD19
- Host Species 1
- Mouse
- Target 2
- CD28
- Host Species 2
- Mouse
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Chronic lymphocytic leukemia and Follicular lymphoma.
Target
- Target 1
- CD19
- Gene ID
- 930
- UniProt ID
- P15391
- Alternative Names
- CD19; CD19 molecule; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4
- Target 2
- CD28
- Gene ID
- 940
- UniProt ID
- B4E0L1
- Alternative Names
- CD28; CD28 molecule; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
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Datasheet
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COA
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