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CD19 & CD28

Anti-CD19 & CD28 Products

anti-CD19 immunotoxin HD37 (scFv)-PE (AGTO-L047E)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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Anti-Human CD19 Recombinant Antibody (TAB-108CL) (TAB-108CL)
- Derivation: Human
- Species Reactivity: Human
- Type: Antibody
- Application: FC, ADCC, FuncS
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Humanized Anti-CD28 Recombinant Antibody (clone Lulizumab) (TAB-H46)
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized V-kappa
- Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
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Mouse Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1611CL-F(E)) (TAB-1611CL-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: Depletion, FuncS
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Mouse Anti-CD28 Recombinant Antibody (clone 1C6) (PABL-365)
- Derivation: Mouse
- Species Reactivity: canine
- Type: Mouse IgG1
- Application: WB, ELISA, FuncS
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Human Anti-CD19 Recombinant Antibody (HPAB-0418LY) (HPAB-0418LY)
- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG1
- Application: Cyt, BLI, FC, FuncS, ELISA, WB, RIA
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Mouse Anti-CD19 Recombinant Antibody (TAB-1611CL) (TAB-1611CL)
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: Depletion, FuncS
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Anti-Human CD19 Recombinant Antibody scFv Fragment (HD37) (TAB-1620CL-S(P))
- Application: FuncS
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Anti-Human CD19 Recombinant Antibody scFv Fragment (cHD37) (TAB-1621CL-S(P))
- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: FuncS
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Anti-Human CD19 Recombinant Antibody (cHD37) (TAB-1621CL)
- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ADCC, FuncS
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Human Anti-CD19 Recombinant Antibody; scFv Fragment (TAB-1612CL-S(P)) (TAB-1612CL-S(P))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: Depletion, FuncS
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Anti-Human CD19 Recombinant Antibody scFv Fragment (396) (TAB-1625CL-S(P))
- Derivation: Humanized
- Type: Humanized antibody
- Application: Depletion, ELISA
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Anti-Human CD28 Recombinant Antibody scFv Fragment (TGN1412) (TAB-064LC-S(P))
- Derivation: Humanized
- Type: Humanized antibody
- Application: FC
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Human Anti-CD28 Recombinant Antibody; scFv Fragment (TAB-065LC-S(P)) (TAB-065LC-S(P))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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Human Anti-CD28 Recombinant Antibody; scFv Fragment (TAB-066LC-S(P)) (TAB-066LC-S(P))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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Anti-Human CD28 Recombinant Antibody scFv Fragment (ChTN228) (TAB-068LC-S(P))
- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: FC, ELISA
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Mouse Anti-CD19 Recombinant Antibody (clone ME-CD20) (MOB-0278MZ)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC
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Mouse Anti-CD28 Recombinant Antibody (clone DD29.1) (MOB-0354MZ)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
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Human Anti-CD19 Recombinant Antibody (TAB-1612CL) (TAB-1612CL)
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: Depletion, FuncS
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Human Anti-CD19 Recombinant Antibody (TAB-1613CL) (TAB-1613CL)
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: Cyt, FC, FuncS, Inhib
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Human Anti-CD19 Recombinant Antibody (TAB-1614CL) (TAB-1614CL)
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: FuncS
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Human Anti-CD19 Recombinant Antibody (TAB-1616CL) (TAB-1616CL)
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB
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Human Anti-CD19 Recombinant Antibody (TAB-1617CL) (TAB-1617CL)
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB
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Human Anti-CD19 Recombinant Antibody (TAB-1618CL) (TAB-1618CL)
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB
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Human Anti-CD19 Recombinant Antibody (TAB-1619CL) (TAB-1619CL)
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB
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Mouse Anti-CD19 Recombinant Antibody (clone 32B9) (MOB-1087z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, FC, ICC, IF, FuncS
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Humanized Anti-CD19 Recombinant Antibody (TAB-891) (TAB-891)
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
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Anti-Human CD19 Recombinant Antibody (TAB-H17) (TAB-H17)
- Derivation: Humanized
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, IP, Neut, FuncS, ELISA, FC, WB
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Afuco™ Anti-Human CD19 ADCC Recombinant Antibody (MDX-1342), ADCC Enhanced (AFC-104CL)
- Derivation: Human
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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Anti-Human CD19 Recombinant Antibody Fab Fragment (396) (TAB-1625CL-F(E))
- Derivation: Humanized
- Type: Humanized antibody
- Application: Depletion, ELISA
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Anti-Human CD19 Recombinant Antibody (396) (TAB-1625CL)
- Derivation: Humanized
- Type: Humanized antibody
- Application: Depletion, ELISA
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Human Anti-CD19 Recombinant Antibody (TAB-1626CL) (TAB-1626CL)
- Type: Fully human antibody
- Application: Depletion
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Human Anti-CD19 Recombinant Antibody (TAB-1627CL) (TAB-1627CL)
- Type: Fully human antibody
- Application: Depletion
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Mouse Anti-CD19 Recombinant Antibody; scFv Fragment (TAB-1613CL-S(P)) (TAB-1613CL-S(P))
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: Depletion, FuncS
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Mouse Anti-CD19 Recombinant Antibody; scFv Fragment (TAB-1614CL-S(P)) (TAB-1614CL-S(P))
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FuncS
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Human Anti-CD19 Recombinant Antibody; scFv Fragment (TAB-1616CL-S(P)) (TAB-1616CL-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB
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Human Anti-CD19 Recombinant Antibody; scFv Fragment (TAB-1617CL-S(P)) (TAB-1617CL-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB
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Human Anti-CD19 Recombinant Antibody; scFv Fragment (TAB-1618CL-S(P)) (TAB-1618CL-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB
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Human Anti-CD19 Recombinant Antibody; scFv Fragment (TAB-1619CL-S(P)) (TAB-1619CL-S(P))
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB
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Mouse Anti-CD28 Recombinant Antibody (clone CBLS-209) (MOB-0424ZL)
- Species Reactivity: Human, Non-Human Primates
- Type: Mouse IgG1
- Application: FC, IP, WB, IHC, FuncS
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Anti-Human CD19 Recombinant Antibody Fab Fragment (cHD37) (TAB-1621CL-F(E))
- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: FuncS
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Human Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1612CL-F(E)) (TAB-1612CL-F(E))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: Depletion, FuncS
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Human Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1613CL-F(E)) (TAB-1613CL-F(E))
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: Depletion, FuncS
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Human Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1614CL-F(E)) (TAB-1614CL-F(E))
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: FuncS
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Human Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1616CL-F(E)) (TAB-1616CL-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB
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Human Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1617CL-F(E)) (TAB-1617CL-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB
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Human Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1618CL-F(E)) (TAB-1618CL-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB
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Human Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1619CL-F(E)) (TAB-1619CL-F(E))
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB
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Anti-Human CD19 Recombinant Antibody Fab Fragment (HD37) (TAB-1620CL-F(E))
- Application: FuncS
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Mouse Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1622CL-F(E)) (TAB-1622CL-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC, Apop, ADCC, FuncS
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Mouse Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1623CL-F(E)) (TAB-1623CL-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC
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Anti-Human CD19 Recombinant Antibody Fab Fragment (381) (TAB-1624CL-F(E))
- Application: FC, Inhib, ELISA
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Mouse Anti-CD28 Recombinant Antibody (clone ANC28.1/5D10); F(ab')₂ Fragment (DrMAB-981)
- Species Reactivity: Human
- Type: Mouse IgG1 F(ab')2, κ
- Application: Agonist, Stim, Neu, FC
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Mouse Anti-CD28 Recombinant Antibody (clone 1C6); scFv Fragment (PSBL-365)
- Derivation: Mouse
- Species Reactivity: Canine
- Type: Mouse scFv
- Application: WB, ELISA, FuncS
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Mouse Anti-CD28 Recombinant Antibody (clone 1C6); Fab Fragment (PFBL-365)
- Derivation: Mouse
- Species Reactivity: canine
- Type: Mouse Fab
- Application: WB, ELISA, FuncS
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Mouse Anti-CD28 Recombinant Antibody (clone AV7); scFv Fragment (FAMAB-0013-CN-S(P))
- Species Reactivity: Chicken, Turkey
- Type: Mouse scFv
- Application: FC
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Human Anti-CD28 Recombinant Antibody (clone FR255734); scFv Fragment (HPAB-0132CQ-S(P))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, IHC, Block
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Mouse Anti-CD19 Recombinant Antibody (clone Taplitumomab) (TAB-174)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
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Anti-CD19 immunotoxin HD37 (IgG)-RTA (AGTO-G076R)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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anti-CD19 immunotoxin HD37 (scFv)-DT (AGTO-L047D)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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Anti-CD19 immunotoxin HD37 (IgG)-Sap (AGTO-G076S)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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anti-CD19 immunotoxin HD37 (scFv)-RTA (AGTO-L047R)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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Mouse Anti-CD19 Recombinant Antibody; scFv Fragment (TAB-1611CL-S(P)) (TAB-1611CL-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: Depletion, FuncS
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Anti-CD19 immunotoxin HD37 (IgG)-PE (AGTO-G076E)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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Anti-CD19 immunotoxin HD37 (IgG)-DT (AGTO-G076D)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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Anti-CD28 Antibody-Cytokine Fusion Protein, IL2-IgG (15E8) (ACFP-SH130)
- Target: CD28
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Mouse
- Cytokine 1 Species: Human
- Molecule Class: IL2-IgG2a
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Anti-CD28 Antibody-Cytokine Fusion Protein, TNF-IgG (15E8) (ACFP-SH131)
- Target: CD28
- Species Reactivity: Human
- Cytokine 1: TNF
- Host: Mouse
- Cytokine 1 Species: Human
- Molecule Class: TNF-IgG2a
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Anti-CD19 immunotoxin HD37 (IgG)-PAP (AGTO-G076P)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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anti-CD19 immunotoxin HD37 (scFv)-Sap (AGTO-L047S)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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anti-CD19 immunotoxin HD37 (scFv)-PAP (AGTO-L047P)
- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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Recombinant Humanized Anti-CD28 Single Domain Antibody (FAMAB-0320YC-VH) (FAMAB-0320YC-VH)
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized VH
- Application: ELISA
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Anti-Human CD19 Recombinant Antibody (HD37) (TAB-1620CL)
- Application: FuncS
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Mouse Anti-CD19 Recombinant Antibody (TAB-1622CL) (TAB-1622CL)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC, Apop, ADCC, FuncS
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Mouse Anti-CD19 Recombinant Antibody (TAB-1623CL) (TAB-1623CL)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
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Anti-Human CD19 Recombinant Antibody (381) (TAB-1624CL)
- Application: FC, Inhib, ELISA
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Mouse Anti-CD19 Recombinant Antibody; scFv Fragment (TAB-1622CL-S(P)) (TAB-1622CL-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC, Apop, ADCC, FuncS
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Mouse Anti-CD19 Recombinant Antibody; scFv Fragment (TAB-1623CL-S(P)) (TAB-1623CL-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
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Anti-Human CD19 Recombinant Antibody scFv Fragment (381) (TAB-1624CL-S(P))
- Application: FC, Inhib, ELISA
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Anti-CD19 fully human monoclonal antibody MDX-1342 (Gly-011CL)
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Recombinant Anti-Human CD19 Antibody (Fc glycosylation/Low fucosylated) (Gly-061LC)
- Host Species: Human
- Specificity: Human
- Type: Chimeric antibody (mouse/human)
- Classification: Fc glycosylation/Low fucosylated
- Glycosylation site: Asn297 in Fc region
- Glycoform (ratio): GN-GN-M-(M-GN)2
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Recombinant Anti-Human CD19 Antibody (Fc glycosylation/Low fucosylated) (Gly-061LC-1)
- Host Species: Human
- Specificity: Human
- Type: Chimeric antibody (mouse/human)
- Classification: Fc glycosylation/Low fucosylated
- Glycosylation site: Asn297 in Fc region
- Glycoform (ratio): GN-GN-M-(M-GN)2
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Chicken Anti-CD19 Polyclonal IgY (BRD-0100MZ)
- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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Recombinant Anti-CD19 × Anti-CD28 Bispecific Antibody (Fab₂) (FAB-L059)
- Targets: CD19 & CD28
- Type: Fab₂
- Application: FuncS, Promising therapeutic agent
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Anti-CD19 (hBU12)-Mc-MMAF ADC (SGN-19A) (ADC-L034)
- Target: CD19
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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Anti-CD19 (clone hBU12)-vcPAB-MMAE ADC (ADC-150CL)
- Target: CD19
- Linker: VC-PAB (valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
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Anti-CD19 (hBU12)-mcMMAF ADC (ADC-017LCT)
- Target: CD19
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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Anti-CD19 (clone BU12)-MC-MMAF ADC (ADC-189CL)
- Target: CD19
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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Anti-CD19 (Denintuzumab)-Mc-MMAF ADC (ADC-175LCT)
- Target: CD19
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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Anti-CD19 (clone huB4)-mc-MMAF ADC (ADC-045LZY)
- Target: CD19
- Linker: mc (maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
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Anti-CD19 (clone huB4)-SMCC-DM1 ADC (ADC-157LZY)
- Target: CD19
- Linker: SMCC (4-[N-maleimidomethyl] cyclohexane-1 carboxylhydrazide).
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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Anti-CD19 (clone MDX1435)-vc-duocarmycin ADC (ADC-163LZY)
- Target: CD19
- Linker: VC (valine-citrulline)
- Drug: duocarmycin
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Anti-CD19 (clone B496)-SPP-DM1 ADC (ADC-181LZY)
- Target: CD19
- Linker: SPP (N-succinimidyl-4-(2-pyridyldithio)pentanoate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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Anti-CD19 (clone B496)-MCC-DM1 ADC (ADC-182LZY)
- Target: CD19
- Linker: MCC (Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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Anti-CD19 (clone B496)-mc-vc-PABC-MMAE ADC (ADC-183LZY)
- Target: CD19
- Linker: mc-VC-PABC (maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAE (monomethyl auristatin E)
Compare

Anti-CD19 (clone B496)-mc-MMAF ADC (ADC-184LZY)
- Target: CD19
- Linker: mc (maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
Compare

Recombinant Anti-Human CD19 Antibody (Fc glycosylation/Non fucosylated) (Gly-141LC)
- Host Species: Human
- Specificity: Human
- Type: Humanized antibody
- Classification: Fc glycosylation/Non fucosylated
- Glycosylation site: Asn297 in Fc region
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Recombinant Anti-Human CD19 Antibody (Fc glycosylation/Non fucosylated) (Gly-141LC-1)
- Host Species: Human
- Specificity: Human
- Type: Humanized antibody
- Classification: Fc glycosylation/Non fucosylated
- Glycosylation site: Asn297 in Fc region
Compare

Anti-CD19 (hBU12)-Mc-MMAE ADC (ADC-019LCT)
- Target: CD19
- Linker: Mc (maleimidocaproyl)
- Drug: MMAE (Monomethyl auristatin E)
Compare

Anti-CD19 (huB4)-SPDB-DM4 ADC (ADC-020LCT)
- Target: CD19
- Linker: SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
- Drug: DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
Compare

Anti-CD19 (hBU12ec)-Mc-vc-PBD ADC (SGN-CD19B) (ADC-L041)
- Target: CD19
- Linker: mc-vc (maleimidocaproyl-valine-alanine)
- Drug: pyrrolobenzodiazepine (PBD) dimers SGD-1882
Compare

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For Research Use Only. Not For Clinical Use.

Background

CD28 (Cluster of Differentiation 28) is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. T cell stimulation through CD28 in addition to the T-cell receptor (TCR) can provide a potent signal for the production of various interleukins (IL-6 in particular).

Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

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