Recombinant Anti-CD22 × Anti-CD79B Bispecific Antibody (Tandem Diabody)
CAT#: TAND-LC001
The anti-CD22/CD79b antibody specifically binds to both CD22 and CD79b, and the antibody can be potentially used in the treatment of autoimmune diseases, such as SLE.
Specifications
- Target
- CD22 & CD79b
- Type
- Tandem Diabody
- Species Reactivity
- Human
- Target 1
- CD22
- Host Species 1
- Rabbit
- Target 2
- CD79b
- Host Species 2
- Rabbit
- Application
- FC
- Related Disease
- Autoimmune disease
Target
- Target 1
- CD22
- Gene ID
- 933
- UniProt ID
- P20273
- Alternative Names
- CD22; CD22 molecule; SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2
- Target 2
- CD79b
- Gene ID
- 974
- UniProt ID
- P40259
- Alternative Names
- CD79B; CD79b molecule, immunoglobulin-associated beta; B29; IGB; AGM6; B-cell antigen receptor complex-associated protein beta chain; Ig-beta; B-cell-specific glycoprotein B29; immunoglobulin-associated B29 protein; CD79b antigen (immunoglobulin-associated beta)
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Q&As
-
Is this antibody suitable for Antibody-Drug Conjugate (ADC) research?
A: Yes, this bispecific antibody targeting CD22 and CD79B is highly suitable for ADC research. Both targets are known to internalize upon antibody binding. By targeting both simultaneously, you can potentially enhance the internalization rate and lysosomal delivery of cytotoxic payloads in B cell malignancies.
-
What specific cell types does this antibody target?
A: This antibody is designed to target B cell lineages, specifically those expressing CD22 and CD79B. These antigens are commonly found on B cell lymphomas and leukemias, making this product a valuable tool for researching targeted therapies for B cell-derived hematological cancers.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
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Datasheet
MSDS
COA
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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