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    CD22 & CD79B

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    Anti-CD22 & CD79B Products

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    • Anti-CD22 (clone hu10F4)-MCC-DM1 ADC (ADC-027LZY)
      • Target: CD22
      • Linker: MCC (4-(N-maleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-CD22-mc-vc-PABc-MMAE ADC (ADC-033LZY)
      • Target: CD22
      • Linker: mc-VC-PABc(maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
      • Drug: MMAE (monomethyl auristatin E)
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    • Anti-CD79b-vc-MMAE ADC (ADC-034LZY)
      • Target: CD79b
      • Linker: VC(Valine-citrulline)
      • Drug: MMAE (monomethyl auristatin E)
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    • Anti-CD79b-MCC-DM1 ADC (ADC-084LZY)
      • Target: CD79b
      • Linker: MCC (4-(Nmaleimidomethyl)cyclohexane-1 carboxylate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-CD79b-mc-MMAF ADC (ADC-085LZY)
      • Target: CD79b
      • Linker: mc(maleimidocaproyl)
      • Drug: MMAF(monomethyl auristatin F)
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    • Anti-CD79b (clone SN8)-MCC-DM1 ADC (ADC-202LZY)
      • Target: CD79b
      • Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-cyCD79b (clone 10D10)-MCC-DM1 ADC (ADC-216LZY)
      • Target: cyCD79b
      • Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate))
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-CD22 (RFB4)-mcc-DM1 ADC (ADC-028LCT)
      • Target: CD22
      • Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD22-mc-vc-PABc-NMS249 ADC (ADC-097LZY)
      • Target: CD22
      • Linker: mc-VC-PABc (maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
      • Drug: NMS249
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    • Anti-CD79 (bSN8)-mcc-DM1 ADC (ADC-089LCT)
      • Target: CD79b
      • Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD22 (clone 10F4v3)-MCC-DM1 ADC (ADC-194LZY)
      • Target: CD22
      • Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-CD79b (clone SN8)-SPP-DM1 ADC (ADC-201LZY)
      • Target: CD79b
      • Linker: SPP(N-succinimidyl-4-(2-pyridyldithio)pentanoate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-CD79b (clone ch2F2)-SMCC-DM1 ADC (ADC-202CL)
      • Target: CD79b
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD79b (clone hu2F2.D7)-SMCC-DM1 ADC (ADC-203CL)
      • Target: CD79b
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    For Research Use Only. Not For Clinical Use.


    Background

    Predicted to enable CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Involved in B cell activation; negative regulation of B cell receptor signaling pathway; and regulation of endocytosis. Located in early endosome and recycling endosome.
    CD22 & CD79B
    CD79B (CD79b Molecule) is a Protein Coding gene. Diseases associated with CD79B include Agammaglobulinemia 6, Autosomal Recessive and Agammaglobulinemia, Non-Bruton Type. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Innate Immune System. Gene Ontology (GO) annotations related to this gene include transmembrane signaling receptor activity.
    CD22 & CD79B
    Related Signaling Pathways
    BCR Signaling Pathway BCR Signaling Pathway
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