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    CD22 & CD79B

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    Anti-CD22 & CD79B Products

    • Anti-CD79b (clone ch2F2)-SMCC-DM1 ADC (ADC-202CL)
      • Target: CD79b
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD79b (clone hu2F2.D7)-SMCC-DM1 ADC (ADC-203CL)
      • Target: CD79b
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD22 (clone hu10F4)-MCC-DM1 ADC (ADC-027LZY)
      • Target: CD22
      • Linker: MCC (4-(N-maleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-CD79 (bSN8)-mcc-DM1 ADC (ADC-089LCT)
      • Target: CD79b
      • Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD22-mc-vc-PABc-NMS249 ADC (ADC-097LZY)
      • Target: CD22
      • Linker: mc-VC-PABc (maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
      • Drug: NMS249
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    • Anti-CD22 (clone 5E8)-SMCC-DM1 ADC (ADC-214CL)
      • Target: CD22
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD22 (clone 7A2)-SMCC-DM1 ADC (ADC-215CL)
      • Target: CD22
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD22 (clone 10F4v1)-SMCC-DM1 ADC (ADC-216CL)
      • Target: CD22
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD22 (clone 10F4v2)-SMCC-DM1 ADC (ADC-217CL)
      • Target: CD22
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD22 (clone 10F4v3)-MCC-DM1 ADC (ADC-194LZY)
      • Target: CD22
      • Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-CD79b (clone SN8)-SPP-DM1 ADC (ADC-201LZY)
      • Target: CD79b
      • Linker: SPP(N-succinimidyl-4-(2-pyridyldithio)pentanoate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-CD79b (clone SN8)-MCC-DM1 ADC (ADC-202LZY)
      • Target: CD79b
      • Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-cyCD79b (clone 10D10)-MCC-DM1 ADC (ADC-216LZY)
      • Target: cyCD79b
      • Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate))
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-CD22 (RFB4)-mcc-DM1 ADC (ADC-028LCT)
      • Target: CD22
      • Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD22-MC-MMAF ADC (ADC-032LCT)
      • Target: CD22
      • Linker: Mc (maleimidocaproyl)
      • Drug: MMAF (Monomethyl auristatin F)
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    • Anti-CD22-MCC-DM1 ADC (ADC-033LCT)
      • Target: CD22
      • Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD22-mc-vc-PABc-MMAE ADC (ADC-033LZY)
      • Target: CD22
      • Linker: mc-VC-PABc(maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
      • Drug: MMAE (monomethyl auristatin E)
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    • Anti-CD79b-vc-MMAE ADC (ADC-034LZY)
      • Target: CD79b
      • Linker: VC(Valine-citrulline)
      • Drug: MMAE (monomethyl auristatin E)
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    • Anti-CD79b-MCC-DM1 ADC (ADC-084LZY)
      • Target: CD79b
      • Linker: MCC (4-(Nmaleimidomethyl)cyclohexane-1 carboxylate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-CD79b-mc-MMAF ADC (ADC-085LZY)
      • Target: CD79b
      • Linker: mc(maleimidocaproyl)
      • Drug: MMAF(monomethyl auristatin F)
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    For Research Use Only. Not For Clinical Use.


    Background

    The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component.
    CD22 & CD79B
    CD22 (CD22 Molecule) is a Protein Coding gene. Diseases associated with CD22 include refractory hematologic cancer and colon lymphoma. Among its related pathways are Immune System and Downstream signaling events of B Cell Receptor (BCR). GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is VCAM1.
    CD22 & CD79B
    Related Signaling Pathways
    BCR Signaling Pathway BCR Signaling Pathway
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