Recombinant Anti-CD22 × Anti-saporin Bispecific Antibody (Fab2)
CAT#: FAB-L077
Recombinant Anti-CD22 × Anti-saporin Bispecific Antibody (Fab2) is composed of the Fab of the anti-CD22 monoclonal antibody and Fab of an antibody specific for saporin. A linker is added between the two Fab. The bispecific antibody is somewhat smaller than a whole IgG, and therefore it clears from the blood naturally at a faster rate. This BsAb can be used in pretargeting system and deliver immunotoxin to tumor cells. It was designed for the treatment of B cells lymphoma.
Specifications
- Target
- CD22 & saporin
- Type
- Fab2
- Species Reactivity
- Human
- Target 1
- CD22
- Host Species 1
- Mouse
- Target 2
- saporin
- Host Species 2
- Mouse
- Application
- FuncS, Pretargeting system for immunotoxin delivery
- Related Disease
- B cells lymphoma
Target
- Target 1
- CD22
- Gene ID
- 933
- UniProt ID
- P20273
- Alternative Names
- CD22; CD22 molecule; SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2
- Target 2
- saporin
- Alternative Names
- saporin
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