Recombinant Anti-CD28 × Anti-FOLR1 Bispecific Antibody (Fab2) (CAT#: FAB-L038)
Recombinant Anti-CD28 × Anti-FOLR1 Bispecific Antibody (Fab2) is composed of the Fab of the anti-CD28 monoclonal antibody and Fab of an antibody specific for FOLR1. A linker is added between the two Fab. This BsAb can retarget of T cells to tumor cells. It was designed for the treatment of Ovarian carcinom.
Specific Inquiry
Specifications
- Target
- CD28 & FOLR1
- Type
- Fab2
- Species Reactivity
- Human
- Target 1
- CD28
- Host Species 1
- Mouse
- Target 2
- FOLR1
- Host Species 2
- Mouse
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Ovariancarcinom
Target
- Target 1
- CD28
- Gene ID
- 940
- UniProt ID
- B4E0L1
- Alternative Names
- CD28; CD28 molecule; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
- Target 2
- FOLR1
- Gene ID
- 2348
- UniProt ID
- A0A024R5H1
- Alternative Names
- FOLR1; folate receptor 1 (adult); FBP; FOLR; folate receptor alpha; FR-alpha; KB cells FBP; folate binding protein; folate receptor, adult; adult folate-binding protein; ovarian tumor-associated antigen MOv18
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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