Recombinant Anti-CD33 × Anti-CD3 Bispecific Antibody (Fab2)
CAT#: FAB-L004
Recombinant Anti-CD33 & Anti-CD3 Bispecific Antibody (Fab2) is composed of the Fab of the anti-CD33 monoclonal antibody and Fab of an antibody specific for CD3. A linker is added between the two Fab. The bispecific antibody is somewhat smaller than a whole IgG and therefore it can be cleared from the blood naturally at a faster rate. It was designed for the treatment of acute myelogenous leukemia (AML).
Specifications
- Target
- CD33 & CD3
- Type
- Fab2
- Species Reactivity
- Human
- Target 1
- CD33
- Host Species 1
- Human
- Target 2
- CD3
- Host Species 2
- Mouse
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Acute myelogenous leukemia (AML)
Target
- Target 1
- CD33
- Gene ID
- 945
- UniProt ID
- P20138
- Alternative Names
- CD33; CD33 molecule; p67; SIGLEC3; SIGLEC-3; myeloid cell surface antigen CD33; gp67; CD33 antigen (gp67); sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3
- Target 2
- CD3
- Gene ID
- 916
- UniProt ID
- P07766
- Alternative Names
- CD3E; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
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See other products for "CD33 & CD3"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAND-LC006 | Recombinant Anti-CD33 × Anti-CD3 Bispecific Antibody (Tandem Diabody, CD33xCD3 scBsDb) | FC | Tandem Diabody |
| TAND-LC010 | Recombinant Human Anti-CD33 × Anti-CD3 Bispecific Antibody (Tandem Diabody) | FC | Tandem Diabody |
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