CD33 & CD3
CD33 (CD33 Molecule) is a Protein Coding gene. Diseases associated with CD33 include Gallbladder Lymphoma and Extracutaneous Mastocytoma. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Innate Immune System. Gene Ontology (GO) annotations related to this gene include receptor activity and carbohydrate binding. An important paralog of this gene is SIGLEC6.
The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: WB
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FuncS
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FuncS
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human, Chimpanzee, Cynomolgus monkey
- Type: Chimeric (mouse/human) Fab
- Application: ELISA
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human, Chimpanzee, Cynomolgus monkey
- Type: Chimeric (mouse/human) Fab
- Application: ELISA
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human, Chimpanzee, Cynomolgus monkey
- Type: Chimeric (mouse/human) Fab
- Application: ELISA
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human, Chimpanzee, Cynomolgus monkey
- Type: Chimeric (mouse/human) Fab
- Application: ELISA
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human, Chimpanzee, Cynomolgus monkey
- Type: Chimeric (mouse/human) Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC, ELISA
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Inhib
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Human Fab
- Application: ELISA
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- Derivation: Human
- Species Reactivity: Human, Cynomolgus monkey
- Type: Human Fab
- Application: ELISA
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- Derivation: Human
- Species Reactivity: Human, Cynomolgus monkey
- Type: Human Fab
- Application: ELISA
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- Derivation: Human
- Species Reactivity: Human, Cynomolgus monkey
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human, Mammal
- Type: Mouse Fab
- Application: ELISA, FC
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- Species Reactivity: Human, Mammal
- Type: Mouse Fab
- Application: ELISA, FC
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- Species Reactivity: Human, Mammal
- Type: Mouse Fab
- Application: ELISA, FC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC
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- Species Reactivity: Human, Cynomolgus
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, IP, ChiP, Neut, ELISA
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- Species Reactivity: Human
- Type: Camelid VHH
- Application: ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA, FC
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