CD33 & CD3
Loading...Anti-CD33 & CD3 Products
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Loading...- Anti-CD33 Recombinant Antibody (TAB-756) (TAB-756)
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
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- Mouse Anti-CD33 Recombinant Antibody (TAB-119LC) (TAB-119LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, IF, RIA
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- Mouse Anti-CD3 Recombinant Antibody (TAB-0416CL) (TAB-0416CL)
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- Application: FC, IB, ELISA
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- Mouse Anti-CD3 Recombinant Antibody scFv Fragment (TAB-0416CL-S(P)) (TAB-0416CL-S(P))
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- Application: IB, ELISA, FC, FuncS
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- Mouse Anti-CD33 Recombinant Antibody (TAB-130LC) (TAB-130LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
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- Humanized Anti-Human CD3 Recombinant Antibody (TAB-0418CL)
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- Type: Humanized Antibody
- Application: ELISA, FC, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA, FC, IF, IHC, IP, FuncS
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- Mouse Anti-CD33 Recombinant Antibody (TAB-122LC) (TAB-122LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Cyt
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- Anti-Human CD33 Recombinant Antibody (TAB-123LC)
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- Type: Human antibody
- Application: FC
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- Chimeric Anti-Human CD3 Recombinant Antibody (TAB-072LC)
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
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- Anti-Human CD3 Recombinant Antibody (TAB-071LC)
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, FC, IP, FuncS, IF, Neut, IHC
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- Human Anti-CD3 Recombinant Antibody (TAB-075LC) (TAB-075LC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, FC
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- Human Anti-CD3 Recombinant Antibody (TAB-076LC) (TAB-076LC)
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
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- Human Anti-CD3 Recombinant Antibody (TAB-077LC) (TAB-077LC)
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
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- Human Anti-CD3 Recombinant Antibody (TAB-078LC) (TAB-078LC)
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
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- Human Anti-CD3 Recombinant Antibody (TAB-079LC) (TAB-079LC)
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Humanized (from mouse) IgG4, κ
- Application: IF, IP, Neut, FuncS, ELISA, FC, WB
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- Rat Anti-CD3 Recombinant Antibody (clone 17A2) (MOB-0202MC)
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- Species Reactivity: Mouse
- Type: Rat IgG2b, κ
- Application: FC, IHC, IP, Activ, CMCD, Depletion
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- Human Anti-Human CD3 Recombinant Antibody Fab Fragment (TAB-0532CL-F(E))
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- Type: Human antibody
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- Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-075LC-S(P)) (TAB-075LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-076LC-S(P)) (TAB-076LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
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- Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-077LC-S(P)) (TAB-077LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
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- Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-078LC-S(P)) (TAB-078LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
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- Chimeric Anti-Human CD3 Recombinant Antibody scFv Fragment (TAB-072LC-S(P))
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
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- Anti-Human CD3 Recombinant Antibody Fab Fragment (TAB-071LC-F(E))
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
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- Chimeric Anti-Human CD3 Recombinant Antibody Fab Fragment (TAB-072LC-F(E))
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
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- Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-075LC-F(E)) (TAB-075LC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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- Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-077LC-F(E)) (TAB-077LC-F(E))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA
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- Anti-Human CD33 Recombinant Antibody Fab Fragment (TAB-123LC-F(E))
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- Type: Human antibody
- Application: FC
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- Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-078LC-F(E)) (TAB-078LC-F(E))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA
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- Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-081LC-F(E)) (TAB-081LC-F(E))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA
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- Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-083LC-F(E)) (TAB-083LC-F(E))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA
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- Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-084LC-F(E)) (TAB-084LC-F(E))
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- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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- Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-076LC-F(E)) (TAB-076LC-F(E))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA
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- Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-079LC-F(E)) (TAB-079LC-F(E))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA
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- Human Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-080LC-F(E)) (TAB-080LC-F(E))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Humanized Fab
- Application: ELISA
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- Human Anti-Human CD3 Recombinant Antibody (TAB-0532CL)
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- Type: Human antibody
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- Recombinant Anti-human CD33 VHH Single Domain Antibody (NAB-321-sdAb)
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- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, IP, ChiP, Neut, ELISA
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- Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-127LC-F(E)) (TAB-127LC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC
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- Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-126LC-F(E)) (TAB-126LC-F(E))
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse Fab
- Application: ELISA, FC
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- Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-121LC-F(E)) (TAB-121LC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-122LC-F(E)) (TAB-122LC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Mouse Anti-CD33 Recombinant Antibody (TAB-131LC) (TAB-131LC)
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse IgG
- Application: ELISA, FC
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- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-0422CL-S(P)) (TAB-0422CL-S(P))
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse scFv
- Application: ELISA
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- Anti-Mouse CD3 Recombinant Antibody Fab Fragment (Dow2) (TAB-0365CL-F(E))
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- Application: IP, IB, FuncS
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- Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (TAB-132LC-S(P)) (TAB-132LC-S(P))
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse scFv
- Application: ELISA, FC
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- Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (TAB-133LC-S(P)) (TAB-133LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
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- Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (TAB-134LC-S(P)) (TAB-134LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
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- Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (TAB-135LC-S(P)) (TAB-135LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
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- Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-128LC-F(E)) (TAB-128LC-F(E))
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse Fab
- Application: ELISA, FC
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- Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-129LC-F(E)) (TAB-129LC-F(E))
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse Fab
- Application: ELISA, FC
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- Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-130LC-F(E)) (TAB-130LC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC
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- Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-131LC-F(E)) (TAB-131LC-F(E))
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse Fab
- Application: ELISA, FC
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- Mouse Anti-CD33 Recombinant Antibody (TAB-124LC) (TAB-124LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
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- Mouse Anti-CD33 Recombinant Antibody (TAB-125LC) (TAB-125LC)
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse IgG
- Application: ELISA, FC
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- Mouse Anti-CD33 Recombinant Antibody (TAB-126LC) (TAB-126LC)
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse IgG
- Application: ELISA, FC
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- Mouse Anti-CD33 Recombinant Antibody (TAB-127LC) (TAB-127LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
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- Mouse Anti-CD33 Recombinant Antibody (TAB-128LC) (TAB-128LC)
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse IgG
- Application: ELISA, FC
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- Mouse Anti-CD33 Recombinant Antibody (TAB-129LC) (TAB-129LC)
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse IgG
- Application: ELISA, FC
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- Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-124LC-F(E)) (TAB-124LC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC
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- Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-125LC-F(E)) (TAB-125LC-F(E))
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse Fab
- Application: ELISA, FC
Compare
- Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-119LC-F(E)) (TAB-119LC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, IF, RIA
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- Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-120LC-F(E)) (TAB-120LC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-073LC-F(E)) (TAB-073LC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-074LC-F(E)) (TAB-074LC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-073LC-S(P)) (TAB-073LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-074LC-S(P)) (TAB-074LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-070LC-F(E)) (TAB-070LC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Mouse Anti-CD3 Recombinant Antibody (TAB-0422CL) (TAB-0422CL)
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse IgG
- Application: ELISA
Compare
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-070LC-S(P)) (TAB-070LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Mouse Anti-CD3 Recombinant Antibody (TAB-070LC) (TAB-070LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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- anti-CD33 immunotoxin M195 (IgG)-PE (AGTO-L050E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- anti-CD33 immunotoxin M195 (IgG)-Gel (AGTO-L050G)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- Anti-Mouse CD3 Recombinant Antibody scFv Fragment (Dow2) (TAB-0365CL-S(P))
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- Application: IP, IB, FuncS
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- Anti-Mouse CD3 Recombinant Antibody (Dow2) (TAB-0365CL)
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- Application: FC, IHC
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- Anti-CD33 immunotoxin (scFv)-Gel (AGTO-G008G)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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- Anti-CD33 immunotoxin (scFv)-PE (AGTO-G008E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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- Mouse Anti-CD33 Recombinant Antibody (TAB-120LC) (TAB-120LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Cyt
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- Mouse Anti-CD33 Recombinant Antibody (TAB-121LC) (TAB-121LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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- Mouse Anti-CD3 Recombinant Antibody (TAB-073LC) (TAB-073LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
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- Mouse Anti-CD3 Recombinant Antibody (TAB-074LC) (TAB-074LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
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- Anti-CD33 (h2H12)-mc-vc-PBD ADC (ADC-062LCT)
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- Target: CD33
- Linker: mc-VC (maleimidocaproyl-valine-citrulline)
- Drug: pyrrolobenzodiazepine (PBD) dimers
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- Anti-CD33 (h2H12)-vc-PABC-MMAE ADC (ADC-063LCT)
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- Target: CD33
- Linker: VC-PABC (valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
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- Anti-CD33 (clone h2H12ec)-mc-vc-PBD ADC (ADC-044LZY)
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- Target: CD33
- Linker: mc-VC (maleimidocaproyl-valine-alanine)
- Drug: pyrrolobenzodiazepine (PBD) dimers
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- Anti-CD33 (clone h2H12) ADC (ADC-093CL)
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- Target: CD33
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- Anti-CD33 (clone hP67.6)-calicheamicin ADC (ADC-143CL)
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- Target: CD33
- Drug: calicheamicin
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- Anti-CD33 (HuM195)-SPDB-DM4 ADC (ADC-061LCT)
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- Target: CD33
- Linker: SPDB
- Drug: DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
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- Anti-CD33 (clone hP67.6)-AcBut-Calicheamicin ADC (ADC-007LZY)
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- Target: CD33
- Linker: AcBut (4-(4-acetylphenoxy)butanoic acid)
- Drug: Calicheamicin
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- Anti-CD33 (clone huMy9-6)-SPDB-DM4 ADC (ADC-023LZY)
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- Target: CD33
- Linker: SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
- Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
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- Anti-CD33 (HuM195)-AcBut-Calicheamicin ADC (ADC-056LCT)
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- Target: CD33
- Linker: AcBut
- Drug: Calicheamicin
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- Anti-CD33mAb-DOTA-G3FC ADC (ADC-057LCT)
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- Target: CD33
- Linker: DOTA-G3FC
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- Anti-CD33mAb-DOTA-NCS ADC (ADC-058LCT)
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- Target: CD33
- Linker: DOTA-NCS
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- Anti-CD33mAb-DOTA-SH ADC (ADC-059LCT)
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- Target: CD33
- Linker: DOTA-SH
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- Anti-CD33 (Gemtuzumab)-hydrazone-Calicheamicin ADC (ADC-060LCT)
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- Target: CD33
- Linker: hydrazone
- Drug: Calicheamicin
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- Anti-CD33 (clone h2H12d) ADC (ADC-144CL)
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- Target: CD33
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- Anti-CD33 (clone m2H12)-mc-MMAF ADC (ADC-145CL)
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- Target: CD33
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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For Research Use Only. Not For Clinical Use.
Background
Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state. Preferentially recognizes and binds alpha-2,3- and more avidly alpha-2,6-linked sialic acid-bearing glycans. Upon engagement of ligands such as C1q or syalylated glycoproteins, two immunoreceptor tyrosine-based inhibitory motifs (ITIMs) located in CD33 cytoplasmic tail are phosphorylated by Src-like kinases such as LCK. These phosphorylations provide docking sites for the recruitment and activation of protein-tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2. In turn, these phosphatases regulate downstream pathways through dephosphorylation of signaling molecules. One of the repressive effect of CD33 on monocyte activation requires phosphoinositide 3-kinase/PI3K.
In immunology, the CD3 (cluster of differentiation 3) T-cell co-receptor is a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with a molecule known as the T-cell receptor (TCR) and the ζ-chain to generate an activation signal in T lymphocytes. The TCR, ζ-chain, and CD3 molecules together comprise the TCR complex.