Recombinant Anti-CD45 × Anti-Myosin Bispecific Antibody (Fab2)

CAT#: FAB-L012

Recombinant Anti-CD45 & Anti-myosin Bispecific Antibody (Fab2) is composed of the Fab of the anti-CD45 monoclonal antibody and Fab of an antibody specific for myosin. A linker is added between the two Fab. The bispecific antibody is somewhat smaller than a whole IgG and therefore it can be cleared from the blood naturally at a faster rate. This BsAb can increase the accumulation of CD34+ HSC in the region of injury and improve cardiac function. It was designed for the treatment of myocardial infarction.

Specifications

  • Target
  • CD45 & Myosin
  • Type
  • Fab2
  • Species Reactivity
  • Human
  • Target 1
  • CD45
  • Host Species 1
  • Mouse
  • Target 2
  • Myosin
  • Host Species 2
  • Mouse
  • Application
  • FuncS, Promising therapeutic agent
  • Related Disease
  • Myocardial infarction

Target

  • Target 1
  • CD45
  • Alternative Names
  • LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180
  • Target 2
  • Myosin
  • Alternative Names
  • Myosin; ATP-dependent motor proteins
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