Recombinant Anti-EGFR × Anti-IGFR Bispecific Antibody (Tandem Diabody)
CAT#: TAND-L052
Recombinant Anti-EGFR × Anti-IGFR Bispecific Antibody (Tandem Diabody) is a bispecific fusion protein with four binding sites, two of which bind to antigens of one kind of cells and the other two to the other kind of cells. This BsAb can simultaneously block two receptors. It was designed for the treatment of Colorectal carcinoma, Cervical carcinoma, Breast carcinoma, Pancreatic carcinoma.
Specifications
- Target
- EGFR & IGFR
- Type
- Tandem Diabody
- Species Reactivity
- Human
- Target 1
- EGFR
- Host Species 1
- Human
- Target 2
- IGFR
- Host Species 2
- Human
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Colorectal carcinoma, Cervical carcinoma, Breast carcinoma, Pancreatic carcinoma
Target
- Target 1
- EGFR
- Gene ID
- 1956
- UniProt ID
- P00533
- Alternative Names
- EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1;
- Target 2
- IGFR
- Gene ID
- 3480
- UniProt ID
- P08069
- Alternative Names
- IGF1R; insulin-like growth factor 1 receptor; IGFR; CD221; IGFIR; JTK13; IGF-I receptor; soluble IGF1R variant 1; soluble IGF1R variant 2; insulin-like growth factor I receptor
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