Recombinant Anti-EPCAM × Anti-CD28 Bispecific Antibody (Fab2) (CAT#: FAB-L063)
Recombinant Anti-EPCAM × Anti-CD28 Bispecific Antibody (Fab2) is composed of the Fab of the anti-EPCAM monoclonal antibody and Fab of an antibody specific for CD28. A linker is added between the two Fab. This BsAb can retarget of T cells to tumor cells. It was designed for the treatment of Melanoma.
Specific Inquiry
Specifications
- Target
- EPCAM & CD28
- Type
- Fab2
- Species Reactivity
- Mouse
- Target 1
- EPCAM
- Host Species 1
- Mouse
- Target 2
- CD28
- Host Species 2
- Mouse
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Melanoma
Target
- Target 1
- EPCAM
- Gene ID
- 17075
- UniProt ID
- Q99JW5
- Alternative Names
- EGP; Ly74; gp40; CD326; EGP-2; TROP1; Egp314; Ep-CAM; EpCAM1; Tacsd1; GA733-2; Tacstd1
- Target 2
- CD28
- Gene ID
- 12487
- UniProt ID
- P31041
- Alternative Names
- CD28; CD28 antigen; T-cell-specific surface glycoprotein CD28
Downloads
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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