Recombinant Anti-FcγRIII × Anti-CD30 Bispecific Antibody (CrossMab)
CAT#: CROSS-L006
Recombinant Anti-FcγRIII × Anti-CD30 Bispecific Antibody (CrossMab) has been generated by applying the Crossmab format to generate an IgG shaped entity that binds each ligand with one arm. This BsAb is capable of targeting the tumor and recruiting NK effector cells via binding to the FcγRIII of the NK cell. It was designed for the treatment of Hodgkin's lymphoma.
Specifications
- Target
- FcγRIII & CD30
- Type
- CrossMab
- Species Reactivity
- Human
- Target 1
- FcγRIII
- Host Species 1
- Mouse
- Target 2
- CD30
- Host Species 2
- Mouse
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Hodgkin's Lymphoma
Target
- Target 1
- FcγRIII
- Gene ID
- 2214
- UniProt ID
- M9MML0
- Alternative Names
- FCGR3A; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); CD16; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; FCGRIII; FCRIIIA; low affinity immunoglobulin gamma Fc region receptor III-A; FcgammaRIIIA; CD16a antigen; fc-gamma RIII; Fc-gamma RII
- Target 2
- CD30
- Gene ID
- 943
- UniProt ID
- A5D8T4
- Alternative Names
- TNFRSF8; tumor necrosis factor receptor superfamily, member 8; CD30; Ki-1; D1S166E; tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAND-L051 | Recombinant Anti-FcγRIII × Anti-CD30 Bispecific Antibody (Tandem Diabody) | FuncS, Promising therapeutic agent | Tandem Diabody |
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