Recombinant Anti-FcγRIII × Anti-CD30 Bispecific Antibody (Tandem Diabody)
CAT#: TAND-L051
Recombinant Anti-FcγRIII × Anti-CD30 Bispecific Antibody (Tandem Diabody) is a bispecific fusion protein with four binding sites, two of which bind to antigens of one kind of cells and the other two to the other kind of cells. This BsAb can retarget of NK cells to tumor cells. It was designed for the treatment of Hodgkin's disease.
Specifications
- Target
- FcγRIII & CD30
- Type
- Tandem Diabody
- Species Reactivity
- Human
- Target 1
- FcγRIII
- Host Species 1
- Mouse
- Target 2
- CD30
- Host Species 2
- Mouse
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Hodgkin's disease
Target
- Target 1
- FcγRIII
- Gene ID
- 2214
- UniProt ID
- M9MML0
- Alternative Names
- FCGR3A; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); CD16; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; FCGRIII; FCRIIIA; low affinity immunoglobulin gamma Fc region receptor III-A; FcgammaRIIIA; CD16a antigen; fc-gamma RIII; Fc-gamma RII
- Target 2
- CD30
- Gene ID
- 943
- UniProt ID
- A5D8T4
- Alternative Names
- TNFRSF8; tumor necrosis factor receptor superfamily, member 8; CD30; Ki-1; D1S166E; tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| CROSS-L006 | Recombinant Anti-FcγRIII × Anti-CD30 Bispecific Antibody (CrossMab) | FuncS, Promising therapeutic agent | CrossMab |
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