Recombinant Anti-ITGAV × Anti-Ad fiber knob Bispecific Antibody (Fab₂)

Name: Recombinant Anti-ITGAV × Anti-Ad fiber knob Bispecific Antibody (Fab2)
SKU: FAB-L082
Rating: 5 (1 reviews)

CAT#: FAB-L082

Recombinant Anti-ITGAV × Anti-Ad fiber receptor Bispecific Antibody (Fab₂) is composed of the Fab of the anti-ITGAV monoclonal antibody and Fab of an antibody specific for adfiberreceptor. A linker is added between the two Fab. The bispecific antibody is somewhat smaller than a whole IgG, and therefore it clears from the blood naturally at a faster rate. This BsAb can retarget of adenoviral vectors to tumour cells. It can be used in cancer gene therapy to transfer a therapeutic gene into tumour cells aiming at selective and efficient cell killing.

Specifications

Target
ITGAV & Ad fiber knob

Type
Fab₂

Species Reactivity
Human

Target 1
ITGAV

Host Species 1
Mouse

Target 2
Ad fiber knob

Host Species 2
Mouse

Application
FuncS, Gene delivery in gene therapy

Related Disease
Angiogenesis

Target

Target 1
ITGAV

Gene ID
3685

UniProt ID
P06756

Alternative Names
ITGAV; integrin, alpha V; CD51; MSK8; VNRA; VTNR; integrin alpha-V; integrin alphaVbeta3; vitronectin receptor subunit alpha; antigen identified by monoclonal antibody L230; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

Target 2
Ad fiber knob

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Datasheet

Datasheet - FAB-L082.pdf

MSDS

MSDS - FAB-L082.pdf

COA

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