ITGAV & Ad fiber knob
Anti-ITGAV & Ad fiber knob Recombinant Antibody Products
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG2 - kappa
- Application: Inhib, Agonist
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA, ICC, IF, IHC, IP, FuncS
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, FC
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- Derivation: Human
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: ELISA, FC, IP, FuncS, IF, Neut
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: ELISA, IP, FC, FuncS, IF, Neut
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- Species Reactivity: Human
- Type: IgG1
- Application: Inhib, ICC/IF, BL, FC, ELISA, IP
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- Species Reactivity: Human, African Green Monkey, Rabbit, Bovine
- Type: IgG1, κ
- Application: FC, IHC-Fr, ICC, IP, ELISA, Depletion, BL, Adhesion
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- Species Reactivity: Human
- Type: IgG2a, κ
- Application: FC, IF, ELISA, BL, IP
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- Species Reactivity: Human, Mouse, Rat
- Type: IgG2a
- Application: IP, FC, BL
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- Species Reactivity: Human
- Type: IgG1
- Application: ICC/IF, FC, IP, IHC-Fr, BL
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- Species Reactivity: Human
- Type: IgG1
- Application: CyTOF, BL, FC, IP, ICC
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- Species Reactivity: Mouse
- Type: IgG1, κ
- Application: FC, FuncS, IP, Neut
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA, FuncS
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- Target: ITGAV
- Target Species: Human, African Green Monkey, Rabbit, Bovine
- Application: IP, Protein Purification
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, IHC
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, FC
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- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IF, IP
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-P
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, IF
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, FC, IHC
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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- Species Reactivity: Human
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, FC, IHC-Fr, IP
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, WB, IHC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ADCC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA, FC, ADCC
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- Species Reactivity: Human
- Application: FC, IHC-Fr, PP
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: Neut, FuncS
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- Target: αvβ integrin receptor
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Humanized from Mouse
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IgG2-IL2
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: Cyt, ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: Cyt, ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: Cyt, ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: Cyt, ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, FuncS
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- Target: αvβ integrin receptor
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Humanized from Mouse
- Cytokine 1 Species: Human
- Molecule Class: L Kappa; IL2-IgG2
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: Neut, FuncS
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- Target: integrin alphaV
- Drug: DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
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- Target: Integrin αγ
- Linker: SPDB
- Drug: DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, FC
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- Targets: ITGAV & Ad fiber knob
- Type: Fab2
- Application: FuncS, Gene delivery in gene therapy
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For Research Use Only. Not For Clinical Use.
Ad fiber knob is expressed in adenovirus.
This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. Note that the integrin alpha 5 and integrin alpha V chains are produced by distinct genes.