Recombinant Anti-MET × Anti-VEGFR-2 Bispecific Antibody (scFv2-Fc) (CAT#: BSAB-MZ017)
Recombinant Anti-Met × Anti-VEGFR-2 bsAb in the scFv-Fc format was generated, in which two scFvs, one for VEGFR-2 and one for Met, were fused to the N-terminus of the heterodimeric Fc. It is capable of inhibiting the downstream signaling and tube formation stimulated by the two receptors, c-Met and VEGFR-2, in human endothelial cells.
Specific Inquiry
Specifications
- Target
- MET & VEGFR-2
- Type
- scFv2-Fc
- Species Reactivity
- Human
- Target 1
- MET
- Host Species 1
- Human
- Target 2
- VEGFR-2
- Host Species 2
- Human
- Application
- FC
- Related Disease
- Gastric cancer
Target
- Target 1
- MET
- Gene ID
- 4233
- UniProt ID
- A0A024R759
- Alternative Names
- MET; MET proto-oncogene, receptor tyrosine kinase; HGFR; AUTS9; RCCP2; c-Met; hepatocyte growth factor receptor; SF receptor; HGF receptor; HGF/SF receptor; proto-oncogene c-Met; scatter factor receptor; tyrosine-protein kinase Met; met proto-oncogene tyrosine kinase
- Target 2
- VEGFR-2
- Gene ID
- 3791
- UniProt ID
- A0A024RD88
- Alternative Names
- KDR; kinase insert domain receptor; FLK1; CD309; VEGFR; VEGFR2; vascular endothelial growth factor receptor 2; soluble VEGFR2; fetal liver kinase 1; fetal liver kinase-1; protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factor receptor; kinase insert domain receptor (a type III receptor tyrosine kinase);
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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