Recombinant Anti-MUC1 × Anti-CD28 Bispecific Antibody (Fab2) (CAT#: FAB-L072)
Recombinant Anti-MUC1 × Anti-CD28 Bispecific Antibody (Fab2) is composed of the Fab of the anti-MUC1 monoclonal antibody and Fab of an antibody specific for CD28. A linker is added between the two Fab. The bispecific antibody is somewhat smaller than a whole IgG and therefore it clears from the blood naturally at a faster rate. This BsAb can enhance the cytotoxicity of LAK cells.It was designed for the treatment of bile duct carcinoma.
Specific Inquiry
Specifications
- Target
- MUC1 & CD28
- Type
- Fab2
- Species Reactivity
- Human
- Target 1
- MUC1
- Host Species 1
- Mouse
- Target 2
- CD28
- Host Species 2
- Mouse
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Bile duct carcinoma
Target
- Target 1
- MUC1
- Gene ID
- 4582
- UniProt ID
- P15941
- Alternative Names
- MUC1; mucin 1, cell surface associated; EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC; mucin-1; episialin; DF3 antigen; H23 antigen; cancer antigen 15-3; krebs von den Lungen-
- Target 2
- CD28
- Gene ID
- 940
- UniProt ID
- B4E0L1
- Alternative Names
- CD28; CD28 molecule; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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