1 0
Cart
    Inquiry
    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    MUC1 & CD28

    Loading...

    Anti-MUC1 & CD28 Products

    + Filter
    Loading...
    • Anti-CanAg (clone huC242)-SMCC-[3H]DM1 ADC (ADC-213LZY)
      • Target: CanAg
      • Linker: SMCC (4-[N-maleimidomethyl] cyclohexane-1 carboxylhydrazide).
      • Drug: [3H]DM1([3H]N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
      Go to compare Compare
    • Anti-Mucin1-DM4 ADC (ADC-112LZY)
      • Target: Mucin1
      • Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
      Go to compare Compare
    • Anti-CanAg (clone huC242)-SPDB-[3H]DM4 ADC (ADC-214LZY)
      • Target: CanAg
      • Linker: SPDB(N-succinimidyl 4-(2-pyridyldithio)butyrate)
      • Drug: [3H]DM4([3H]N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
      Go to compare Compare
    • Anti-CanAg (clone huC242)-SPP-DM1 ADC (ADC-209LZY)
      • Target: CanAg
      • Linker: SPP(N-succinimidyl 4-(2-pyridyldithio)pentanoate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
      Go to compare Compare
    • Anti-CanAg (clone huC242)-SMCC-DM1 ADC (ADC-102LZY)
      • Target: CanAg
      • Linker: SMCC (4-[N-maleimidomethyl] cyclohexane-1 carboxylhydrazide).
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
      Go to compare Compare
    • Anti-CanAg (huC242)-Sulfo-SPDB-DM4 ADC (ADC-010LCT)
      • Target: CanAg
      • Linker: sulfo-SPDB (sulfo-N-succinimidyl 4-(2-pyridyldithio)butyrate
      • Drug: DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
      Go to compare Compare
    • Anti-CanAg (huC242)-SPP-DM1 ADC (ADC-012LCT)
      • Target: CanAg
      • Linker: SPP (N-succinimidyl-4-(2-pyridyldithio)pentanoate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
      Go to compare Compare
    • Anti-CanAg (clone huC242)-SPP-[3H]DM1 ADC (ADC-212LZY)
      • Target: CanAg
      • Linker: SPP(N-succinimidyl 4-(2-pyridyldithio)pentanoate)
      • Drug: [3H]DM1([3H]N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
      Go to compare Compare
    • Anti-CA6 (clone huDS6)-SPDB-DM4 ADC (ADC-012LZY)
      • Target: CA6, a specific glycol-epitope of MUC-1
      • Linker: SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
      • Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
      Go to compare Compare
    • Anti-CAIX-mcc-MMAE ADC (ADC-013LCT)
      • Target: CAIX, Carbonic anhydrase IX
      • Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
      • Drug: MMAE (Monomethyl auristatin E)
      Go to compare Compare
    • Anti-CanAg (huC242)-SMCC-DM1 ADC (ADC-009LCT)
      • Target: CanAg
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
      Go to compare Compare
    View More Products

    Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

    More Infomation

    Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

    For Research Use Only. Not For Clinical Use.


    Background

    This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.
    MUC1 & CD28
    The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    MUC1 & CD28
    Related Diseases
    Rheumatoid Arthritis Rheumatoid Arthritis
    Systemic Lupus Erythematosus Systemic Lupus Erythematosus
    Allograft Rejection Allograft Rejection
    Autoimmune Thyroid Disease Autoimmune Thyroid Disease
    Graft-versus-Host Disease Graft-versus-Host Disease
    Maturity Onset Diabetes of the Young Maturity Onset Diabetes of the Young
    Go to compare

    Go to compare