Recombinant Anti-PLAP × Anti-CD3 Bispecific Antibody (Fab2) (CAT#: FAB-L020)
Recombinant Anti-PLAP × Anti-CD3 Bispecific Antibody (Fab2) is composed of the Fab of the anti-PLAP monoclonal antibody and Fab of an antibody specific for CD3. A linker is added between the two Fab. This BsAb can retarget of Tcells to tumor cells. It was designed for the treatment of Ovarian cancer .
Specific Inquiry
Specifications
- Target
- PLAP & CD3
- Type
- Fab2
- Species Reactivity
- Human
- Target 1
- PLAP
- Host Species 1
- Mouse
- Target 2
- CD3
- Host Species 2
- Mouse
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Ovarian cancer
Target
- Target 1
- PLAP
- Gene ID
- 250
- UniProt ID
- P05187
- Alternative Names
- ALPP; alkaline phosphatase, placental; ALP; PALP; PLAP; PLAP-1; alkaline phosphatase, placental type; glycerophosphatase; alkaline phosphomonoesterase; placental alkaline phosphatase 1; alkaline phosphatase Regan isozyme
- Target 2
- CD3
- Gene ID
- 916
- UniProt ID
- P07766
- Alternative Names
- CD3E; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
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CrossMab Products
Tandem Diabody Products
CAT | Product Name | Application | Type |
---|---|---|---|
CROSS-L042 | Recombinant Anti-PLAP × Anti-CD3 Bispecific Antibody (CrossMab) | FuncS, Promising therapeutic agent | CrossMab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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