Recombinant Anti-VEGF × Anti-ANG2 Bispecific Antibody (Bi-Single Domain Antibody)
CAT#: NANO-L001
Recombinant Anti-VEGFA × Anti-Ang2 Bispecific Antibody (Bi-Single Domain Antibody) comprises two monomeric VH-like binding entities of different specificities that are fused to each other in a bivalent-bispecific manner. Bi-Single Domain Antibody is only consisted of the VHHs. The loss of light chain and constant fragment in bi-Single Domain Antibody does not eliminate their functional antigen-binding capacity, but even endows them non-substitutable advantage in application. This BsAb is capable of inhibiting two proangiogenics and a combined blockade of them has a greater inhibitory efficacy compared with inhibition of either factor alone. It was designed for the treatment of diseases that are associated with VEGFA- and/or Ang2- mediated effects on angiogenesis are disclosed.
Specifications
- Target
- VEGF & ANG2
- Type
- Bi-Single Domain Antibody
- Species Reactivity
- Human
- Target 1
- VEGF
- Host Species 1
- Llama
- Target 2
- ANG2
- Host Species 2
- Llama
- Application
- FuncS, Promising therapeutic agent
- Related Disease
- Diseases that are associated with VEGFA- and/or Ang2- mediated effects on angiogenesis are disclosed
Target
- Target 1
- VEGF
- Gene ID
- 7422
- UniProt ID
- P15692
- Alternative Names
- VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor
- Target 2
- ANG2
- Gene ID
- 285
- UniProt ID
- O15123
- Alternative Names
- ANGPT2; angiopoietin 2; ANG2; AGPT2; angiopoietin-2; ANG-2; Tie2-ligand; angiopoietin-2B; angiopoietin-2a
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for NANO-L001. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "VEGF & ANG2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAND-L030 | Recombinant Anti-VEGF × Anti-ANG2 Bispecific Antibody (Tandem Diabody) | FuncS, Promising therapeutic agent | Tandem Diabody |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: FC, IHC, FuncS, Inhib, Cyt
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
-2-1.png)
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: WB, ELISA, FuncS, Inhib, PK, IP, SPR
-3.jpg)
Application: Neut
Application: Neut, FuncS, IHC, ELISA, FC, Inhib
Application: Inhib, FC, WB
Application: IF, ICC, WB, IHC-P, IP
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
