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VEGF & ANG2

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Anti-VEGF & ANG2 Products

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For Research Use Only. Not For Clinical Use.


Background

The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.
VEGF is a signaling protein that stimulates angiogenesis (the formation of new blood vessels). It plays a crucial role in normal development and in diseases like cancer and macular degeneration.
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