HPSTI scaffold protein anti-Human Neutrophil elastase (CAT#: SHP-L252)
The HPSTI that bound Neutrophil elastase was isolated from the library using Phage display; techonology. After affinity maturation, HPSTI variants were identified having affinities for Neutrophil elastase as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
Specific Inquiry
Normal Tissue
RNA Expression

Figure 1 Bone marrow
(Hematopoietic cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73774/170937_B_6_4.jpg
(Hematopoietic cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73774/170937_B_6_4.jpg

Figure 2 RNA cell line category: Cell line enriched (THP-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197561-ELANE
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197561-ELANE

Figure 2 RNA cell line category: Cell line enriched (THP-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197561-ELANE
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197561-ELANE
Specifications
- Scaffold Name
- HPSTI
- Origin
- Human pancreatic secretory trypsin inhibitor (PSTI)
- Core Structure
- α/β-loops (56)
- Variable Regions
- 6 to 8 aa
- Target
- Neutrophil elastase
- Species Reactivity
- Human
- Expression Host
- BL21 (DE3) cells
- Applications
- ELISA; IHC; Microscopy; FC; WB; FuncS
Target
- Alternative Names
- human pancreatic secretory trypsin inhibitor (PSTI); HPSTI; GE; NE; HLE; HNE; ELA2; SCN1; PMN-E
- Gene ID
- 1991
- UniProt ID
- P08246
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
CAT | Product Name | Application | Type |
---|---|---|---|
DrMAB-1041 | Mouse Anti-ELANE Recombinant Antibody (clone YC039); Fab Fragment | ELISA | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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