Hypothemycin

Name: Hypothemycin
SKU: ADCsR-186CL
Rating: 5 (1 reviews)

CAT#: ADCsR-186CL

Exhibits antifungal and cytotoxic activity against some tumor cell lines partly attributed to inhibition of Ras-inducible genes. Inhibits proliferation of mouse and human T cells and modulates production of cytokines during T cell activation. Facilitates the ubiquitinylation process of cyclin D1. Has been identified as a potent and selective inhibitor of threonine/tyrosine-specific kinase, MEK, and other protein kinases that contain a conserved cysteine residue in the ATP-binding site in both in vitro and in vivo studies. HCT-116: IC50=0,0026 uM; PSN1 : IC50=0,26 uM; T98G : IC50=2,6 uM; A549 : IC50=0,26 uM (preliminary laboratory results). Journal of Natural Products (2011), 74(5), 1126-1131.

Specifications

Formula
C19H22O8

CAS No.
76958-67-3

Molecular Weight
378,37 g/mol

Purity
95%

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Datasheet - ADCsR-186CL.pdf

MSDS

MSDS - ADCsR-186CL.pdf

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