PDZ domain anti-GRIA2 (SPD-L155)
The PDZ domain that bound AMPA receptor GluR2 was isolated from the library using Phage display techonology. PDZ domains are modular protein-interaction domains that are specialized for binding to short peptide motifs at the extreme carboxy (C) termini of other proteins, athough they can also have other modes of interaction. After affinity maturation, PDZ domain variants were identified having affinities for AMPA receptor GluR2 as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
Specifications
- Scaffold Name
- PDZ domain
- Origin
- PSD-95 protein
- Core Structure
- β-sheet
- Target
- AMPA receptor GluR2
- Species Reactivity
- Human
- Expression Host
- E. coli
- Applications
- ELISA; IHC; Microscopy; FC; WB; FuncS
Target
- Alternative Names
- PSD-95 protein; PDZ domain; GLUR2; GLURB; GluA2; HBGR2; GluR-K2
- Entrez Gene ID
- 2891
- UniProt ID
- P42262
For lab research use only, not for diagnostic, therapeutic or any in vivo human use.
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