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  • PE-A*02:01/Human HDAC1 (RMLPHAPGV) MHC Tetramer

PE-A*02:01/Human HDAC1 (RMLPHAPGV) MHC Tetramer (CAT#: MHC-LC1937)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human HDAC1 of peptide RMLPHAPGV covering 371-379 and A*02:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


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Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5017/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Figure 2 Cerebral cortex
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68191/152052_A_7_3.jpg
Figure 3 Colon
Figure 3 Colon
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68191/152052_A_7_3.jpg
Figure 4 Liver
Figure 4 Liver
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68191/152052_A_7_4.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68191/152052_A_7_5.jpg
Figure 6 Testis
Figure 6 Testis
(Preleptotene spermatocytes
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68191/152052_A_6_6.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68191/152052_A_8_8.jpg
Figure 8 Tonsil
Figure 8 Tonsil
(Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Squamous epithelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68191/152052_A_6_8.jpg
RNA Expression
Figure 9 RNA cell line category: Low cell line specificity
Figure 9 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000116478-HDAC1

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • Antigen
  • HDAC1
  • Antigen Species
  • Human
  • Peptide
  • RMLPHAPGV
  • Range
  • 371-379
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
  • Alternative Names
  • HDAC1; Histone deacetylase 1; HD1; RPD3; GON-10; RPD3L1

Related Resources

  • Related Diseases

Downloads

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Fab Fragment Antibody

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scFv Fragment Antibody

CAT Product Name Application Type
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MHH-450-S(P) Recombinant Human Anti-human HDAC1 Antibody scFv Fragment IF, Neut, FuncS scFv

Recombinant Antibody

CAT Product Name Application Type
MHH-450 Recombinant Human Anti-human HDAC1 Antibody FC, WB, FuncS IgG
MRO-0716-CN Rabbit Anti-HDAC1 Recombinant Antibody (clone CBACN-255) WB, IF, IHC Rabbit IgG
ZG-0096C Mouse Anti-HDAC1 Recombinant Antibody (clone 4E1) IF/ICC, IHC-P Mouse IgG
VS1-YJ79 Mouse Anti-HDAC1 Recombinant Antibody (clone 10E2) WB, ICC, IF Mouse IgG1
VS3-WK943 Rabbit Anti-HDAC1 Recombinant Antibody (VS3-WK943) WB, ICC, IF, IHC Rabbit IgG

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1571 Rabbit Anti-HDAC1 Recombinant Antibody (clone DS1571AB) WB, IHC-P, ICC Rabbit IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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