PE-A*02:01/Human HLA-E (MVDGTLLLL) MHC Tetramer (CAT#: MHC-LC1930)

• Allele
• A*02:01

• Class
• Class I

• MHC Species
• Human

• Antigen
• HLA-E

• Antigen Species
• Human

• Peptide
• MVDGTLLLL

• Range
• 1-9

• Conjugate
• PE

• Application
• FCM

• Antigen Introduction
• HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008]

• Alternative Names
• HLA-E; HLA class I histocompatibility antigen, alpha chain E precursor; QA1; HLA-6.2

• Gene ID
• 3133

• UniProt ID
• P13747

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