PE-A*68:02/Human LMNB1 (RLAVYIDKV) MHC Tetramer (CAT#: MHC-LC3729)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human LMNB1 of peptide RLAVYIDKV covering 42-50 and A*68:02 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/if_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/if_selected.jpg
Figure 2 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5269/950_C1_1_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5269/950_C1_1_selected.jpg
Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79757/1894_G3_4_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79757/1894_G3_4_selected.jpg
Figure 4 IHC staining of human colon
(Immunohistochemical staining of human colon shows nuclear membrane positivity in glandular and stroma cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/ihc_selected.jpg
(Immunohistochemical staining of human colon shows nuclear membrane positivity in glandular and stroma cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/ihc_selected.jpg
Figure 5 IHC staining of human stomach
(Immunohistochemical staining of human stomach shows strong nuclear membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5269/155655_A_3_1_selected.jpg
(Immunohistochemical staining of human stomach shows strong nuclear membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5269/155655_A_3_1_selected.jpg
Figure 6 IHC staining of human esophagus
(Immunohistochemical staining of human esophagus shows strong nuclear positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79954/171056_B_6_1_selected.jpg
(Immunohistochemical staining of human esophagus shows strong nuclear positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79954/171056_B_6_1_selected.jpg
Figure 7 Cerebral cortex
(Glial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/140330_B_8_5.jpg
(Glial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/140330_B_8_5.jpg
Figure 8 Kidney
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/140330_A_7_4.jpg
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/140330_A_7_4.jpg
Figure 9 Testis
(Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/140330_A_5_6.jpg
(Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/140330_A_5_6.jpg
Figure 10 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/140330_A_8_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/140330_A_8_8.jpg
Figure 11 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113368-LMNB1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113368-LMNB1
Specifications
- Allele
- A*68:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- LMNB1
- Antigen Species
- Human
- Peptide
- RLAVYIDKV
- Range
- 42-50
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
- Alternative Names
- LMNB1; Lamin-B1; LMN; ADLD; LMN2; LMNB
- Gene ID
- 4001
- UniProt ID
- P20700
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1818z | Mouse Anti-LMNB1 Recombinant Antibody (clone 19G6) | ELISA, IHC, WB | Mouse IgG2a, κ |
| MOB-2469CT | Recombinant Mouse anti-Chicken LMNB1 Monoclonal antibody (T70) | WB | |
| VS3-QX694 | Mouse Anti-LMNB1 Recombinant Antibody (clone 5G8-D3-H7) | WB | Mouse IgG2b |
| VS3-FY834 | Recombinant Mouse Anti-LMNB1 Antibody (VS3-FY834) | WB, IP | Mouse IgG |
| VS3-FY852 | Recombinant Rabbit Anti-LMNB1 Antibody (clone R05-8D6) | WB, IHC-P, IP | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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