PE-A*68:02/Human PSMA1 (ELAAHQKKI) MHC Tetramer (CAT#: MHC-LC4294)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human PSMA1 of peptide ELAAHQKKI covering 55-63 and A*68:02 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression

Specifications

  • Allele
  • A*68:02
  • Class
  • Class I
  • Antigen
  • PSMA1
  • Antigen Species
  • Human
  • Peptide
  • ELAAHQKKI
  • Range
  • 55-63
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]
  • Alternative Names
  • PSMA1; Proteasome subunit alpha type-1; NU; HC2; PROS30; HEL-S-275

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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