PE-A*68:02/Human PSMA1 (ELAAHQKKI) MHC Tetramer (CAT#: MHC-LC4294)

• Allele
• A*68:02

• Class
• Class I

• MHC Species
• Human

• Antigen
• PSMA1

• Antigen Species
• Human

• Peptide
• ELAAHQKKI

• Range
• 55-63

• Conjugate
• PE

• Application
• FCM

• Antigen Introduction
• The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]

• Alternative Names
• PSMA1; Proteasome subunit alpha type-1; NU; HC2; PROS30; HEL-S-275

• Gene ID
• 5682

• UniProt ID
• P25786

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