PE-A*69:01/Human GAS1 (GSDGGLDDY) MHC Tetramer
CAT#: MHC-LC4441
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human GAS1 of peptide GSDGGLDDY covering 256-264 and A*69:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to nuclear speckles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36085/765_G1_1_selected.jpg
Normal Tissue
Figure 2 IHC staining of human pancreas
Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/66902/155616_A_2_3_selected.jpg
Normal Tissue
Figure 3 Lymph node
Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/66902/155616_A_7_8.jpg
Normal Tissue
Figure 4 Cerebral cortex
Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/66902/155616_B_7_5.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/66902/155616_A_8_5.jpg
Normal Tissue
Figure 6 Urinary bladder
Urothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/66902/155616_A_6_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/66902/155616_A_6_6.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (AN3-CA, ASC diff, BJ hTERT+, HSkMC, RH-30)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000180447-GAS1
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Specifications
- Allele
- A*69:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- GAS1
- Antigen Species
- Human
- Peptide
- GSDGGLDDY
- Range
- 256-264
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene. [provided by RefSeq, Jul 2008]
- Alternative Names
- GAS1; Growth arrest-specific protein 1 precursor
- Gene ID
- 2619
- UniProt ID
- P54826
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC4440 | PE-A*01:01/Human GAS1 (GSDGGLDDY) MHC Tetramer | FCM |
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