PE-A2/Human GNB2 (ALWDIETGQQTV) MHC Tetramer
CAT#: MHC-LC1965
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human GNB2 of peptide ALWDIETGQQTV covering 167-178 and A2 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10032/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human kidney
Immunohistochemical staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10032/ihc_selected.jpg
RNA Expression
Figure 3 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000172354-GNB2
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Specifications
- Allele
- A2
- Class
- Class I
- MHC Species
- Human
- Antigen
- GNB2
- Antigen Species
- Human
- Peptide
- ALWDIETGQQTV
- Range
- 167-178
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR. [provided by RefSeq, Jul 2008]
- Alternative Names
- GNB2; Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
- Gene ID
- 2783
- UniProt ID
- P62879
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