PE-A2/Human GNB2 (ALWDIETGQQTV) MHC Tetramer (CAT#: MHC-LC1965)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human GNB2 of peptide ALWDIETGQQTV covering 167-178 and A2 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10032/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10032/if_selected.jpg
Figure 2 IHC staining of human kidney
(Immunohistochemical staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10032/ihc_selected.jpg
(Immunohistochemical staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10032/ihc_selected.jpg
Figure 3 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000172354-GNB2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000172354-GNB2
Specifications
- Allele
- A2
- Class
- Class I
- MHC Species
- Human
- Antigen
- GNB2
- Antigen Species
- Human
- Peptide
- ALWDIETGQQTV
- Range
- 167-178
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR. [provided by RefSeq, Jul 2008]
- Alternative Names
- GNB2; Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
- Gene ID
- 2783
- UniProt ID
- P62879
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1465 | Hi-Affi™ Rabbit Anti-GNB2 Recombinant Antibody (clone DS1465AB) | IHC-P, WB, ICC, FC, IP | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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