PE-B*15:01/Human PSMA5 (FHMDPSGTF) MHC Tetramer (CAT#: MHC-LC4424)

• Allele
• B*15:01

• Class
• Class I

• MHC Species
• Human

• Antigen
• PSMA5

• Antigen Species
• Human

• Peptide
• FHMDPSGTF

• Range
• 154-162

• Conjugate
• PE

• Application
• FCM

• Antigen Introduction
• The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]

• Alternative Names
• PSMA5; Proteasome subunit alpha type-5; PSC5; ZETA

• Gene ID
• 5686

• UniProt ID
• P28066

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