Mouse Anti-PSMA5 Recombinant Antibody (VS3-CJ843) (CAT#: VS3-CJ843)

• Immunogen
• Purified His-tagged PSMA5 protein (Fragment)

• Host Species
• Mouse

• Type
• Mouse IgG1

• Specificity
• Human PSMA5

• Species Reactivity
• Human

• Applications
• WB, IF, IHC-P

• Conjugate
• Unconjugated

• Purification
• Protein G affinity purified

• Purity
• >95% as determined by SDS-PAGE

• Format
• Liquid

• Buffer
• PBS, pH 7.3.

• Preservative
• 0.09% Sodium Azide

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• This antibody has been tested for use in Western Blot (1:1000), Immunofluorescence (1:25), Immunohistochemistry-Parraffin (1:25).

• Alternative Names
• PSC5; ZETA

• Gene ID
• 5686

• UniProt ID
• P28066

• Sequence Similarities
• Belongs to the peptidase T1A family.

• Cellular Localization
• Cytoplasm, Nucleus, Proteasome

• Protein Refseq
• NP_001186701.1; NP_001186702.1; NP_001186703.1

• Function
• Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).

Isotype Control

• MOB-065CQ
• Mouse IgG1 Isotype Control Antibody

Secondary Antibody

• 2RD-A1460-YJ
• Goat Anti-Mouse IgG1 Secondary antibody

• 2RD-A1562-YJ
• Rabbit Anti-Mouse IgG1 Secondary antibody (Clone RM106)

Recommended Dilution Buffer

• MRO-0253YJ
• Reconstitution Buffer PBS

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