PE-Gogo-B*0101/Human RACK1 (SRDKTIIMW) MHC Tetramer (CAT#: MHC-LC3043)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human RACK1 of peptide SRDKTIIMW covering 35-43 and Gogo-B*0101 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21676/299_D4_2_selected.jpg

(Immunohistochemical staining of human breast shows cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4288/51894_B_2_4_selected.jpg

(Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4288/51894_B_8_5.jpg

(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4288/51894_A_7_3.jpg

(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4288/51894_A_4_6.jpg

(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4288/51894_A_8_7.jpg

(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4288/51894_A_8_8.jpg

(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000204628-RACK1
Specifications
- Allele
- Gogo-B*0101
- Class
- Class I
- MHC Species
- Gorilla
- Antigen
- RACK1
- Antigen Species
- Human
- Peptide
- SRDKTIIMW
- Range
- 35-43
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- Receptor for activated C kinase 1 (RACK1, also known as guanine nucleotide-binding protein subunit beta-2-like 1 (GNB2L1), is a 32 kDa protein that in humans is encoded by the RACK1 gene.
- Alternative Names
- RACK1; receptor for activated C kinase 1; H12.3; HLC-7; PIG21; GNB2L1; Gnb2-rs1
- Gene ID
- 10399
- UniProt ID
- P63244
Downloads
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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