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    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    PE-Mamu-A1*002:01/Human TAPBPL (GTVRTAVEF) MHC Tetramer (CAT#: MHC-LC4501)

    This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human TAPBPL of peptide GTVRTAVEF covering 183-191 and Mamu-A1*002:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

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    Custom Production

    MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

    Peptide Sequence *:
    Allele Requested *:
    Antigen Species:
    Antigen Molecule:
    Sequence Position:
    Form Requested *:
    Conjugation *:
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    Comments:

    Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 IHC staining of human appendix
    Figure 1 IHC staining of human appendix
    (Immunohistochemical staining of human appendix shows strong membrane positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/39545/83487_A_3_2_selected.jpg
    Figure 2 Cerebral cortex
    Figure 2 Cerebral cortex
    (Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/39545/83487_B_7_5.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/39545/83487_A_7_3.jpg
    Figure 4 Liver
    Figure 4 Liver
    (Cholangiocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/39545/83487_A_7_4.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/39545/83487_A_9_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/39545/83487_A_4_6.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/39545/83487_A_7_8.jpg
    RNA Expression
    Figure 8 RNA cell line category: Cell line enhanced (CAPAN-2, HDLM-2, Karpas-707, RPMI-8226)
    Figure 8 RNA cell line category: Cell line enhanced (CAPAN-2, HDLM-2, Karpas-707, RPMI-8226)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000139192-TAPBPL

    Specifications

    • Allele
    • Mamu-A1*002:01
    • Class
    • Class I
    • MHC Species
    • Macaca
    • Antigen
    • TAPBPL
    • Antigen Species
    • Human
    • Peptide
    • GTVRTAVEF
    • Range
    • 183-191
    • Conjugate
    • PE
    • Application
    • FCM

    Target

    • Antigen Introduction
    • Tapasin, or TAPBP (MIM 601962), is a member of the variable-constant Ig superfamily that links major histocompatibility complex (MHC) class I molecules to the transporter associated with antigen processing (TAP; see MIM 170260) in the endoplasmic reticulum (ER). The TAPBP gene is located near the MHC complex on chromosome 6p21.3. TAPBPL is a member of the Ig superfamily that is localized on chromosome 12p13.3, a region somewhat paralogous to the MHC.[supplied by OMIM, Mar 2008]
    • Alternative Names
    • TAPBPL; Tapasin-related protein; TAPBPR; TAPBP-R

    Downloads

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    CAT Product Name Application Type
    MOB-1540MZ Recombinant Mouse Anti-Human TAPBPL Antibody WB Mouse antibody

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