PE-Mamu-B*003:01/Human ACTG2 (KRGILTLKY) MHC Tetramer
CAT#: MHC-LC2997
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human ACTG2 of peptide KRGILTLKY covering 62-70 and Mamu-B*003:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/41271/103139_B_9_5.jpg
Normal Tissue
Figure 2 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/41271/103139_A_5_6.jpg
Normal Tissue
Figure 3 Smooth muscle
Smooth muscle cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/41271/103139_B_5_7.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (BEWO, BJ hTERT+, BJ hTERT+ SV40 Large T+, HHSteC, SuSa, U-251 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163017-ACTG2
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Specifications
- Allele
- Mamu-B*003:01
- Class
- Class I
- MHC Species
- Macaca
- Antigen
- ACTG2
- Antigen Species
- Human
- Peptide
- KRGILTLKY
- Range
- 62-70
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.[provided by RefSeq, Dec 2010]
- Alternative Names
- ACTG2; Actin, gamma-enteric smooth muscle; ACT; ACTE; VSCM; ACTA3; ACTL3; ACTSG
- Gene ID
- 72
- UniProt ID
- P63267
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COA
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