Protein A-Duocarmycin ADC

CAT#: ADC-187LCT

This ADC product is composed of Protein A conjuagated to Duocarmycins (Protein A-Duocarmycin). It has demonstrated a response in cancer treatment by a MOA (Mechanism of Action) of Bind to DNA minor groove and cause DNA damage.

Specifications

  • Clone
  • Protein A
  • Drug
  • Duocarmycins
  • Drug Class/Description
  • Duocarmycins belong to the minor-groove-binding DNA-alkylating agents (DNA MGBA). The natural duocarmycins are isolated from the culture broth of Streptmyces sp and a series of derivatives has also been synthesized
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