Recombinant Mouse Anti-Human DUSP28 Antibody (clone BG27C8)
CAT#: MOB-2086MZ
This antibody is a recombinant mouse monoclonal antibody which specifically reacts with human DUSP28.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RH-30
Immunofluorescent staining of human cell line RH-30 shows localization to nuclear speckles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47456/1413_E4_2_selected.jpg
Normal Tissue
Figure 2 IHC staining of human testis
Immunohistochemical staining of human testis shows strong cytoplasmic positivity in subset of cells in seminiferous ducts.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69448/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47456/105464_B_7_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47456/105464_A_8_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47456/105464_A_7_5.jpg
Normal Tissue
Figure 6 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47456/105464_A_8_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (U-266/70)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000188542-DUSP28
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Specifications
- Immunogen
- Recombinant full length Human DUSP28 protein purified from Ecoli
- Host Species
- Mouse
- Type
- Mouse antibody
- Specificity
- Human DUSP28
- Species Reactivity
- Human
- Clone
- BG27C8
- Applications
- ELISA, IP, WB
Target
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Highly Specific Antibody
I've been using the Recombinant Anti-Human DUSP28 Antibody for Western blots, and it consistently produces clear, specific bands. The lack of non-specific binding has significantly improved the quality of my results. It's become a reliable component of my experiments, especially when probing for low-abundance proteins.
Reliable in ELISA
I used this antibody in a custom ELISA to quantify DUSP28 levels in serum samples. It showed excellent sensitivity and specificity, enabling me to detect even slight changes in protein concentration. The reproducibility between assays was impressive.
User-Friendly Datasheet
The datasheet provided was comprehensive and easy to follow. It included all necessary information, from storage conditions to recommended dilutions. This clarity made integrating the antibody into my protocols straightforward.
Q&As
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Can this antibody be used to study diseases related to abnormal DUSP28 expression?
A: Yes, the antibody is an excellent tool for researching diseases where DUSP28 is implicated. Abnormal expression of DUSP28 has been associated with certain cancers and metabolic disorders. Researchers can use this antibody to investigate the role of DUSP28 in disease progression and potential therapeutic targets.
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Does Creative Biolabs provide technical support for this antibody?
A: Yes, Creative Biolabs offers comprehensive technical support. Their team can assist with protocol optimization, troubleshooting, and any questions regarding the antibody's applications to ensure successful experimental outcomes.
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How does this antibody aid in signal transduction research?
A: DUSP28 is a dual-specificity phosphatase involved in dephosphorylating key signaling molecules. Using this antibody allows researchers to study the regulatory mechanisms of phosphorylation within signal transduction pathways, providing insights into cellular responses and functions.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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