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Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) (CAT#: Gly-086LC)

This product is a hypergalactosylated human monoclonal antibody with glycoslyated site in Fc region. The glycoengineered antibody GALTR-11 has reduced anti-drug immune respone, it specifically binds TNFα and can be potentially used in the treatment of Rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease and ulcerative colitis.


See more Glyco-Engineering Antibody products for TNF
Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
Figure 1 Tonsil
Figure 1 Tonsil
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78469/168112_A_4_8.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000232810-TNF
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
Figure 2 RNA cell line category: Group enriched (HDLM-2, NB-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000232810-TNF

Glyco-engineering

  • Glycosylation site
  • Asn297 at Fc region
  • Glycoform (ratio)
  • G1F/G2F (80%)
  • Glycosylation Type
  • N-glycosylation
  • Activity
  • Reduced anti-drug immune response

Specifications

  • Target
  • TNFα (Tumor necrosis factor alpha)
  • Host Species
  • Human
  • Type
  • Human antibody
  • Specificity
  • Human
  • Antibody Isotype
  • IgG1
  • Clone
  • GALTR-11
  • Applications
  • ELISA, FC

Target

  • Alternative Names
  • TNF; DIF; TNFA; TNFSF2; TNF-alpha; tumor necrosis factor
  • Related Disease
  • Rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease and ulcerative colitis

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone GALTR-11"

See other products for "TNF"

Mouse Antibody

CAT Product Name Application Type
TAB-768 Anti-TNF alpha Recombinant Antibody (Nerelimomab) FuncS, IF, Neut, ELISA, FC, IP, ICC IgG1
TAB-311CT Anti-Human TNFα/RANKL Recombinant Antibody (8G12) Neut, ELISA, FC
TAB-311CT-F(E) Anti-Human TNFα/RANKL Recombinant Antibody Fab Fragment (8G12) Neut, ELISA, FC
TAB-271CQ Rabbit Anti-TNF Recombinant Antibody (TAB-271CQ) ELISA, Neut Rabbit IgG
TAB-123CQ-S(P) Mouse Anti-TNF Recombinant Antibody; scFv Fragment (TAB-123CQ-S(P)) ELISA, Neut Mouse scFv

Humanized Antibody

CAT Product Name Application Type
TAB-034-F(E) Anti-Human TNF alpha Recombinant Antibody Fab Fragment (Certolizumab Pegol) ELISA, FC, IP, FuncS, IF, Neut, IHC Fab'
TAB-110CQ Anti-Human TNF Recombinant Antibody (CDP571) ELISA Humanized antibody
TAB-114CQ Human Anti-TNF Recombinant Antibody (TAB-114CQ) ELISA, FC, Inhib Humanized antibody
TAB-115CQ Human Anti-TNF Recombinant Antibody (TAB-115CQ) ELISA, FC, Neut Humanized antibody
TAB-118CQ Anti-Human TNF Recombinant Antibody (YHB1411-2) FC, ELISA Humanized antibody

Rat Antibody

CAT Product Name Application Type
TAB-623CL Bovine Anti-TNF Recombinant Antibody (TAB-623CL) Neut Bovine IgG

Chimeric Antibody

CAT Product Name Application Type
TAB-148CQ Anti-Human TNF Recombinant Antibody ELISA Chimeric antibody (mouse/human)
TAB-148CQ-S(P) Anti-Human TNF Recombinant Antibody scFv Fragment ELISA Chimeric antibody (mouse/human)
TAB-402CQ-S(P) Mouse Anti-TNF Recombinant Antibody; scFv Fragment (TAB-402CQ-S(P)) ELISA Mouse scFv
TAB-148CQ-F(E) Anti-Human TNF Recombinant Antibody Fab Fragment ELISA Chimeric antibody (mouse/human)
TAB-402CQ-F(E) Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-402CQ-F(E)) ELISA Chimeric (mouse/human) Fab

Single-domain Antibody

CAT Product Name Application Type
TAB-412CQ Anti-Human TNF Therapeutic Single Domain Antibody (TAR1-5-19) ELISA, Inhib Single domain antibody
TAB-413CQ Anti-Human TNF Therapeutic Single Domain Antibody (VL18) ELISA, WB, Neut Single domain antibody
TAB-414CQ Anti-Human TNF Therapeutic Single Domain Antibody (VL11) ELISA, WB, Neut Single domain antibody
TAB-415CQ Anti-Human TNF Therapeutic Single Domain Antibody (VL18-3L-VL11) ELISA, WB, Neut, FunS Single domain antibody
HPAB-M0402-YC Recombinant Chiloscyllium shark Anti-TNF Single Domain Antibody (3D2) ELISA Chiloscyllium shark vNAR single domain antibody

Human Antibody

CAT Product Name Application Type
TAB-135CQ-F(E) Anti-Human TNF Recombinant Antibody Fab Fragment (AE11-5) ELISA, Neut Human antibody
TAB-136CQ-F(E) Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-136CQ-F(E)) ELISA, Block Human Fab
TAB-137CQ-F(E) Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-137CQ-F(E)) ELISA, FC, IF Human Fab
TAB-138CQ-F(E) Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-138CQ-F(E)) ELISA, FC, IF Human Fab
TAB-140CQ-F(E) Anti-Human TNF Recombinant Antibody Fab Fragment (G1) FC, Neut Human antibody

Fc Glycosylation

CAT Product Name Application Type
Gly-083LC Recombinant Anti-Human TNF Antibody (Fc glycosylation/Non-hyper galactosylated) ELISA, FC Human antibody
Gly-085LC Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) ELISA, FC Human antibody
Gly-087LC Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) ELISA, FC Human antibody
Gly-088LC Recombinant Anti-Human TNF Antibody (Fc glycosylation) ELISA, FC Human antibody
Gly-098LC Recombinant Anti-Human TNF Antibody (Fc glycosylation) ELISA Human antibody

Non-hyper Galactosylated

CAT Product Name Application Type
Gly-083LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Non-hyper galactosylated) ELISA, FC Human antibody

Sialylated IgG Glycan

CAT Product Name Application Type
Gly-085LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) ELISA, FC Human antibody
Gly-163LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) ELISA Chimeric antibody (mouse/human)

Hyper-galactosylated

CAT Product Name Application Type
Gly-086LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) ELISA, FC Human antibody
Gly-087LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Hyper-galactosylated) ELISA, FC Human antibody

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0609MZ Chicken Anti-Tumor Necrosis Factor-α Polyclonal IgY Indirect ELISA, WB Chicken antibody

Neutralizing Antibody

CAT Product Name Application Type
NEUT-2051CQ Mouse Anti-TNF Recombinant Antibody (clone CBL589) ELISA, ICC, Neut Mouse IgG1
NEUT-2052CQ Mouse Anti-TNF Recombinant Antibody (clone CBL570) WB, Neut Mouse IgG2b
NEUT-2053CQ Mouse Anti-TNF Recombinant Antibody (clone CBL571) WB, Neut Mouse IgG1
NEUT-2054CQ Rat Anti-Tnf Recombinant Antibody (clone mAb0856) Neut Rat IgG1
NEUT-2108CQ Mouse Anti-TNF Recombinant Antibody (clone mAb11) ELISA, CyTOF, FC, ICFC, ICC, IF, IHC, Neut Mouse IgG1, κ

Blocking Antibody

CAT Product Name Application Type
NEUT-2057CQ Rat Anti-Tnf Recombinant Antibody (clone XT3) Block, ELISA, IHC, WB Rat IgG1
NEUT-2070CQ Mouse Anti-TNF Recombinant Antibody (clone 4F4) Block, ELISA, ICC, IF, IHC, WB Mouse IgG1
NEUT-2071CQ Rabbit Anti-TNF Recombinant Antibody (clone 6E10) Block, ELISA, IHC, WB Rabbit IgG1
NEUT-2082CQ Mouse Anti-TNF Recombinant Antibody (clone B-C7) Block Mouse IgG1

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4460 Rabbit Anti-TNF Recombinant Antibody (clone SI554DS) ELISA Rabbit IgG
MOR-4461 Rabbit Anti-TNF Recombinant Antibody (clone SI555DS) Neut Rabbit IgG
MOR-4462 Rabbit Anti-TNF Recombinant Antibody (clone SI556DS) FC Rabbit IgG
MOR-4463 Rabbit Anti-TNF Recombinant Antibody (clone SI557DS) FC Rabbit IgG
MOR-4464 Rabbit Anti-TNF Recombinant Antibody (clone SI558DS) FC Rabbit IgG

Recombinant Antibody

CAT Product Name Application Type
HPAB-0151-YC Human Anti-TNF Recombinant Antibody (HPAB-0151-YC) ELISA, Inhib, FuncS Human IgG
HPAB-0046-FY Mouse Anti-TNF Recombinant Antibody (clone 1B7) Neut Mouse IgG
HPAB-1283LY Human Anti-TNF Recombinant Antibody (clone CBL026) ELISA Human IgG
HPAB-0557LY Human Anti-TNF Recombinant Antibody (clone CBL013LY) ELISA Human IgG1
MRO-2233-CN Rabbit Anti-TNF Polyclonal Antibody (MRO-2233-CN) WB, IF, IHC, FC, ELISA Rabbit IgG

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0151-YC-S(P) Human Anti-TNF Recombinant Antibody; scFv Fragment (HPAB-0151-YC-S(P)) ELISA, Inhib, FuncS Human scFv
HPAB-0557LY-S(P) Human Anti-TNF Recombinant Antibody (clone CBL013LY); scfv Fragment ELISA Human scfv
HPAB-1807-FY-F(E) Human Anti-TNF Recombinant Antibody (clone AB164); scFv Fragment Neut Human scFv
HPAB-1808-FY-F(E) Human Anti-TNF Recombinant Antibody (clone AB197); scFv Fragment Neut Human scFv
HPAB-1564WJ-S(P) Mouse Anti-TNF Recombinant Antibody; scFv Fragment (clone 3B10) ELISA, WB, Neut Mouse scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0007-YC-F(E) Human Anti-TNF Recombinant Antibody (clone cA2); Fab Fragment ELISA, Neut Human Fab
HPAB-0321CQ-F(E) Human Anti-TNF Recombinant Antibody (clone mAb A1); Fab Fragment ELISA, Neut Human Fab
HPAB-0322CQ-F(E) Rat Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0322CQ-F(E)) ELISA, FC, Inhib Rat Fab
HPAB-0323CQ-F(E) Rat Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-0323CQ-F(E)) ELISA, FC, Inhib Rat Fab
HPAB-2679LY-F(E) Mouse Anti-TNF Recombinant Antibody; Fab Fragment (HPAB-2679LY-F(E)) ELISA Mouse Fab

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-768 Afuco™ Anti-TNF ADCC Recombinant Antibody (Nerelimomab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody
AFC-TAB-006 Afuco™ Anti-TNF ADCC Recombinant Antibody (Infliximab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-010 Afuco™ Anti-TNF ADCC Recombinant Antibody (AFC-TAB-010), ADCC Enhanced FC, IP, ELISA, Neut, FuncS ADCC enhanced antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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