Recombinant Anti-Trastuzumab Antibody Fab Fragment

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Q&As

1. What are the applications of the Anti-Trastuzumab antibody in research?

   A: The Anti-Trastuzumab antibody Fab fragment is utilized primarily in immunoprecipitation and radioimmunoassay. These applications support the detailed analysis and investigation of breast cancer, particularly involving trastuzumab, a therapeutic agent used for HER2-positive cancers. The Fab fragment's specificity and purity (>95% by SDS-PAGE) make it an excellent choice for precise studies where minimizing host cell protein contamination is crucial.

2. How does HER2 contribute to breast cancer, and how does this antibody aid its study?

   A: HER2 is an oncoprotein whose overexpression is linked to aggressive breast cancer types. By targeting HER2, trastuzumab-mediated therapies inhibit cell proliferation. The Recombinant Anti-Trastuzumab recognizes the trastuzumab antigen, thereby facilitating investigations into HER2-pathology mechanisms, aiding in identifying effective therapeutic strategies by providing insights through detailed immunoassays.

3. What are the unique storage and stability properties of this antibody?

   A: This Fab fragment maintains potency when stored at -20°C, with minimal freeze/thaw cycles. Its stability under these conditions makes it suitable for long-term research projects, ensuring that researchers have access to a consistent, reliable reagent over time.

View the frequently asked questions answered by Creative Biolabs Support.

Cite This Product

To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# MOB-1002-F(E), RRID: AB_3111483)

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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