Recombinant Human Anti-Alphavirus Antibody
CAT#: MHH-53
Recombinant Human Antibody is capable of binding to Alphavirus, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-Alphavirus mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-Alphavirus mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Antibody Isotype
- IgG1
- Species Reactivity
- Alphavirus
- Applications
- Antibody assay: Western blot; Functional Study
Product Property
- Purity
- 90–95% (SDS-PAGE)
- Storage
- ≤6 months at 4°C; ≥6 months at -20°C.
Target
- Alternative Names
- alphavirus
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Specific Viral Detection
We purchased the Recombinant Human Anti-Alphavirus Antibody for our vector-borne disease research. We needed a reagent that could broadly detect Alphavirus antigens in infected cell cultures, and this antibody performed admirably. It showed strong reactivity in immunofluorescence assays, allowing us to visualize the viral distribution within the cytoplasm clearly. The fact that it is a recombinant human antibody helps in reducing background when using anti-human secondary reagents.
High Quality Reagent
The quality of this anti-alphavirus antibody is evident in its performance in neutralization neutralization-related research assays we are developing. It demonstrates high purity and stability, which are essential for our functional studies. We observed a dose-dependent response that aligns perfectly with our viral titer data. This product has become a standard control in our experiments, helping us to benchmark the efficacy of other antiviral compounds we are testing.
Q&As
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We are conducting virology research on arboviruses. Does this antibody detect a specific virus or a broader family, and what is its origin?
A: Thank you for your inquiry regarding our virology catalog. This Recombinant Human Anti-Alphavirus Antibody is designed to recognize antigens from the Alphavirus genus. Being a "Recombinant Human" antibody means the antibody sequence is derived from human immunoglobulin genes, which can be particularly useful for minimizing background in certain assay formats or for specific research applications involving human immune responses.
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Is this antibody suitable for use in research assays to detect viral presence in cell culture supernatants?
A: Yes, this antibody is developed for research use and is suitable for detecting Alphavirus antigens. It can be utilized in various immunoassay formats to identify viral presence in samples such as cell culture supernatants. We recommend performing preliminary validation to determine the optimal concentration for your specific experimental setup and viral strain.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Alphavirus"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-53 | Recombinant Anti-Alphavirus Antibody | ELISA, WB, FC, FuncS | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-53-F(E) | Recombinant Anti-Alphavirus Antibody Fab Fragment | IF, FACS, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-53-S(P) | Recombinant Anti-Alphavirus Antibody scFv Fragment | IF, Neut, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-53-F(E) | Recombinant Human Anti-Alphavirus Antibody Fab Fragment | FC, IP, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-53-S(P) | Recombinant Human Anti-Alphavirus Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1424CQ | Recombinant Mouse Anti-Alphavirus Antibody (VMC81) | ELISA, IF | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1425CQ | Recombinant Mouse Anti-Alphavirus Antibody (VC290) | ELISA | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1426CQ | Recombinant Mouse Anti-Alphavirus Antibody (MRO-1426CQ) | ELISA, IF | Mouse antibody |
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