Recombinant Human Anti-human NBN Antibody
CAT#: MHH-692
Recombinant Human Antibody is bind to Human NBN, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-NBN mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-NBN mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1429/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human testis
Immunohistochemical staining of human testis shows strong nuclear positivity in cells of seminiferous ducts and Leydig cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1429/4888_A_4_6_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1429/4996_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1429/4888_A_9_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1429/4888_A_9_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1429/4888_A_7_5.jpg
Normal Tissue
Figure 7 Cervix
Glandular cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1429/4996_B_7_3.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1429/4888_A_7_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (SK-BR-3)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000104320-NBN
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Specifications
- Immunogen
- Human nibrin
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human nibrin
- Species Reactivity
- Human
- Applications
- Products can be used for: Flow Cytometry; Western blot; Functional Study
Product Property
- Purity
- >95% by HPLC
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "NBN"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-692 | Recombinant Anti-human NBN Antibody | WB, IHC, FuncS | IgG |
| ZG-0481U | Rabbit Anti-Phospho-NBN (S343) Recombinant Antibody (clone 1B4) | ELISA, WB | Rabbit IgG |
| VS3-XY1135 | Mouse Anti-NBN Recombinant Antibody (clone 7E4A2) | ELISA, WB, IHC, FC, ICC | Mouse IgG2a |
| VS3-XY1136 | Mouse Anti-NBN Recombinant Antibody (clone 7E4C2) | ELISA, WB, IHC, FC, ICC | Mouse IgG2a |
| VS3-WK2108 | Rabbit Anti-NBN (pS343) Recombinant Antibody (clone R04-5S5) | WB, ICC, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-692-F(E) | Recombinant Anti-human NBN Antibody Fab Fragment | IP, RIA, FuncS | Fab |
| MHH-692-F(E) | Recombinant Human Anti-human NBN Antibody Fab Fragment | IF, FC, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-692-S(P) | Recombinant Anti-human NBN Antibody scFv Fragment | WB, IF, FuncS | scFv |
| MHH-692-S(P) | Recombinant Human Anti-human NBN Antibody scFv Fragment | WB, ELISA, IHC, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2371 | Hi-Affi™ Recombinant Rabbit Anti-NBN Monoclonal Antibody (DS2371AB) | ICC, IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY198 | AbPlus™ Anti-NBN Magnetic Beads (CBACN-422) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4696 | Anti-NBN Immunohistochemistry Kit | IHC |
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