Src homology domain 3 (SH3) scaffold protein anti-HIV-1 Nef (CAT#: SST-L194)
The Src homology domain 3 (SH3) that bound Nef was isolated from the library using Phage display techonology. After affinity maturation, SH3 variants were identified having affinities (KD=20 mM) for Nef as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
Specific Inquiry
Specifications
- Scaffold Name
- Src homology domain 3 (SH3)
- Origin
- Fyn SH3
- Core Structure
- Mainly β (~60)
- Variable Regions
- 6 or 12 aa
- Target
- Nef
- Species Reactivity
- HIV-1
- Expression Host
- E. coli
- Affinity Constant
- 20 mM
- Applications
- ELISA; IHC; Microscopy; FC; WB; FuncS
Target
- Alternative Names
- Fyn SH3; Src homology domain 3 (SH3); Nef; p27; HIV1gp9
- Gene ID
- 156110
- UniProt ID
- P04601
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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