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    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    Ubiquitin scaffold protein anti-Human HC (CAT#: SUB-L206)

    The ubiquitin that bound HC was isolated from the library using Phage display techonology. After affinity maturation, ubiquitin variants were identified having affinities (KD=10.7 ± 1.0 nM) for HC as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & vesicles.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11571/if_selected.jpg
    Figure 2 IF staining of human cell line A-431
    Figure 2 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17155/623_C4_1_selected.jpg
    Figure 3 IHC staining of human prostate
    Figure 3 IHC staining of human prostate
    (Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59143/ihc_selected.jpg
    Figure 4 IHC staining of human testis
    Figure 4 IHC staining of human testis
    (Immunohistochemical staining of human testis shows cytoplasmic positivity in cells of seminiferus ducts.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10389/ihc_selected.jpg
    Figure 5 IHC staining of human epididymis
    Figure 5 IHC staining of human epididymis
    (Immunohistochemical staining of human epididymis shows distinct cytoplasmic positivity in glandular cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11571/ihc_selected.jpg
    Figure 6 IHC staining of human duodenum
    Figure 6 IHC staining of human duodenum
    (Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in glandular cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17155/ihc_selected.jpg
    Figure 7 IF staining of human cell line U-251 MG
    Figure 7 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol & vesicles.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11571/641_F2_1_blue_red_green.jpg
    Normal Tissue
    Figure 8 Cerebral cortex
    Figure 8 Cerebral cortex
    (Glial cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Neuronal cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous Neuropil
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17155/38923_B_7_5.jpg
    Figure 9 Parathyroid gland
    Figure 9 Parathyroid gland
    (Glandular cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17155/38923_A_2_8.jpg
    Figure 10 Colon
    Figure 10 Colon
    (Glandular cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Peripheral nerve/ganglion
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17155/38923_A_7_3.jpg
    Figure 11 Kidney
    Figure 11 Kidney
    (Cells in glomeruli
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Cells in tubules
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17155/38923_A_8_5.jpg
    Figure 12 Testis
    Figure 12 Testis
    (Cells in seminiferous ducts
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Leydig cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17155/38923_A_6_6.jpg
    RNA Expression
    Figure 13 RNA cell line category: Low cell line specificity
    Figure 13 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000141367-CLTC

    Specifications

    • Scaffold Name
    • Ubiquitin
    • Origin
    • Ubiquitin-like proteins
    • Core Structure
    • α/β (76)
    • Variable Regions
    • 8 aa
    • Target
    • HC
    • Species Reactivity
    • Human
    • Expression Host
    • E. coli
    • Affinity Constant
    • 10.7 ± 1.0 nM
    • Applications
    • ELISA; IHC; Microscopy; FC; WB; FuncS

    Target

    • Alternative Names
    • ubiquitin-like proteins; ubiquitin; Hc; CHC; CHC17; CLH-17; CLTCL2

    Downloads

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    CAT Product Name Application Type
    NAB-674-VHH Recombinant Anti-Human CLTC VHH Single Domain Antibody FA, FC, ICC, ELISA Llama VHH

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