Rabbit Anti-ACADS Recombinant Antibody (VS13-YC12) (CAT#: VS13-YC12)
The Rabbit Anti-ACADS Recombinant Antibody is specific for human, mouse and rat ACADS. ACADS encodes a mitochondrial flavoprotein in the acyl-CoA dehydrogenase family, catalyzing the initial step of fatty acid beta-oxidation. Mutations are linked to SCAD deficiency, with alternative splicing producing different isoforms. The anti-ACADS antibody can be used for Western blot (1/500-1/1000), Immunoprecipitation (1/20).
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoplasm & mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4799/1293_B7_3_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoplasm & mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4799/1293_B7_3_selected.jpg
Figure 2 IF staining of human cell line RT4
(Immunofluorescent staining of human cell line RT4 shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22271/1843_B1_12_cr5af96dd15fa2f_selected.jpg
(Immunofluorescent staining of human cell line RT4 shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22271/1843_B1_12_cr5af96dd15fa2f_selected.jpg
Figure 3 Duodenum
(High expression in duodenum)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22271/49334_A_7_2_val_selected.jpg
(High expression in duodenum)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22271/49334_A_7_2_val_selected.jpg
Figure 4 Kidney
(Bowman's capsule Staining: Medium Intensity: Strong Quantity: <25% Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Collecting ducts Staining: High Intensity: Strong Quantity:>75% Distal tubules Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22271/49334_A_8_5.jpg
(Bowman's capsule Staining: Medium Intensity: Strong Quantity: <25% Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Collecting ducts Staining: High Intensity: Strong Quantity:>75% Distal tubules Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22271/49334_A_8_5.jpg
Figure 5 Testis
(Elongated or late spermatids Staining: High Intensity: Strong Quantity:>75% Leydig cells Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Round or early spermatids Staining: High Intensity: Strong Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22271/49334_A_4_6.jpg
(Elongated or late spermatids Staining: High Intensity: Strong Quantity:>75% Leydig cells Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Round or early spermatids Staining: High Intensity: Strong Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22271/49334_A_4_6.jpg
Figure 6 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22271/49334_B_8_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22271/49334_B_8_5.jpg
Figure 7 Colon
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22271/49334_A_9_3.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22271/49334_A_9_3.jpg
Figure 8 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22271/49334_A_9_4.jpg
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22271/49334_A_9_4.jpg
Figure 9 RNA cell line category: Cell line enhanced (HMC-1)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000122971-ACADS
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000122971-ACADS
Specifications
- Immunogen
- Recombinant human ACADS.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat ACADS
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IP
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunoprecipitation (IP): 1/20
Target
- Alternative Names
- Acyl-CoA Dehydrogenase Short Chain; Acyl-Coenzyme A Dehydrogenase, C-2 To C-3 Short Chain; Butyryl-CoA Dehydrogenase; SCAD; Short-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial; Mitochondrial Short-Chain Specific Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenase, C-2 To C-3 Short Chain;
- Gene ID
- 35
- UniProt ID
- P16219
- Long Name
- Acyl-CoA Dehydrogenase Short Chain
- Function
- Signal transduction
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0405MZ | Mouse Anti-ACADS Recombinant Antibody (clone 8F2BC6) | IF, ELISA, WB | Mouse IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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