AbPlus™ Anti-ACTN4 Magnetic Beads (VS-0724-YC1368)
CAT#: VS-0724-YC1368
The AbPlus Anti-ACTN4 Magnetic Beads (VS-0724-YC1368) is an innovative affinity resin which is bound with anti-ACTN4 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of ACTN4 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nuclear bodies.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1873/63_D5_1_selected.jpg
Normal Tissue
Figure 2 IHC staining of human liver
Immunohistochemical staining of human liver shows strong cytoplasmic and membranous positivity in bile duct cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1873/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1873/7921_B_8_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1873/7921_A_8_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1873/7921_A_9_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1873/7921_A_9_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1873/7921_A_6_6.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1873/7921_A_8_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (A549)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130402-ACTN4
❮
❯
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-ACTN4 specific antibody
- Target
- ACTN4
- Immunogen
- Recombinant human alpha Actinin 4/ACTN4 fragment derived from E. coli.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008]
- Alternative Names
- Actinin Alpha 4; Focal Segmental Glomerulosclerosis 1; Non-Muscle Alpha-Actinin 4; Alpha-Actinin-4; ACTININ-4; FSGS1; FSGS;
- Gene ID
- 81
- UniProt ID
- O43707
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0724-YC1368. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ACTN4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0357CL | Anti-ACTN4 Recombinant Antibody | IHC, ELISA | |
| TAB-0357CL-S(P) | Anti-ACTN4 Recombinant Antibody scFv Fragment | IHC, ELISA | |
| TAB-0357CL-F(E) | Anti-ACTN4 Recombinant Antibody Fab Fragment | IHC, ELISA | |
| TAB-0651CLV | Mouse Anti-ACTN4 Recombinant Antibody (TAB-0651CLV) | WB, IHC | Mouse IgG |
| TAB-0651CLV-S(P) | Mouse Anti-ACTN4 Recombinant Antibody; scFv Fragment (TAB-0651CLV-S(P)) | WB, IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0057 | Hi-Affi™ Rabbit Anti-ACTN4 Recombinant Antibody (clone DS57AB) | ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0073-CN | Mouse Anti-ACTN4 Recombinant Antibody (clone N01) | ELISA, IHC | Mouse IgG2 |
| HPAB-0187-LSX | Mouse Anti-ACTN4 Recombinant Antibody (HPAB-0187-LSX) | ELISA, WB, IHC | Mouse IgG |
| HPAB-0188-LSX | Mouse Anti-ACTN4 Recombinant Antibody (HPAB-0188-LSX) | ELISA, WB, IHC | Mouse IgG |
| HPAB-0189-LSX | Mouse Anti-ACTN4 Recombinant Antibody (HPAB-0189-LSX) | ELISA, WB, IHC | Mouse IgG |
| HPAB-0190-LSX | Mouse Anti-ACTN4 Recombinant Antibody (HPAB-0190-LSX) | ELISA, WB, IHC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0073-CN-F(E) | Mouse Anti-ACTN4 Recombinant Antibody (clone N01); Fab Fragment | ELISA, IHC | Mouse Fab |
| HPAB-0187-LSX-F(E) | Mouse Anti-ACTN4 Recombinant Antibody Fab Fragment (HPAB-0187-LSX-F(E)) | ELISA, WB, IHC | Mouse Fab |
| HPAB-0188-LSX-F(E) | Mouse Anti-ACTN4 Recombinant Antibody Fab Fragment (HPAB-0188-LSX-F(E)) | ELISA, WB, IHC | Mouse Fab |
| HPAB-0189-LSX-F(E) | Mouse Anti-ACTN4 Recombinant Antibody Fab Fragment (HPAB-0189-LSX-F(E)) | ELISA, WB, IHC | Mouse Fab |
| FAMAB-0057JF-F(E) | Human Anti-ACTN4 Recombinant Antibody (clone A2); Fab Fragment | FC, WB, IHC, ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0187-LSX-S(P) | Mouse Anti-ACTN4 Recombinant Antibody scFv Fragment (HPAB-0187-LSX-S(P)) | ELISA, WB, IHC | Mouse scFv |
| HPAB-0188-LSX-S(P) | Mouse Anti-ACTN4 Recombinant Antibody scFv Fragment (HPAB-0188-LSX-S(P)) | ELISA, WB, IHC | Mouse scFv |
| HPAB-0189-LSX-S(P) | Mouse Anti-ACTN4 Recombinant Antibody scFv Fragment (HPAB-0189-LSX-S(P)) | ELISA, WB, IHC | Mouse scFv |
| HPAB-0190-LSX-S(P) | Mouse Anti-ACTN4 Recombinant Antibody scFv Fragment (HPAB-0190-LSX-S(P)) | ELISA, WB, IHC | Mouse scFv |
| FAMAB-0057JF-S(P) | Human Anti-ACTN4 Recombinant Antibody (clone A2); scFv Fragment | FC, WB, IHC, ELISA, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF314 | A*02:01/Human ACTN4 (K5N) (FIASNGVKLV) MHC Pentamer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0057JF | Human Anti-ACTN4 Recombinant Antibody (clone A2) | WB, ELISA, IHC, IF | Human IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY125 | Anti-ACTN4 Immunohistochemistry Kit | IHC | |
| VS-0525-XY126 | Anti-Mouse ACTN4 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: WB, ELISA, FC, IHC, IP
Application: WB, ELISA, FuncS, IB, FC, SPR, Apop
Application: FC, IHC-Fr, IP, ELISA, Block
Application: ELISA, IHC, FC, IP, IF, BL
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, WB, FC
Application: ELISA, FC, Neut, Inhib
Application: ELISA, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
