Human Anti-ACTN4 Recombinant Antibody (clone A2) (CAT#: FAMAB-0057JF)

Figure 1 Confocal immunofluorescence microscopy showed the meningitic E. coli co-located with EGFR and ACTN4.

Identification of ACTN4 as an EGFR interacting protein in hBMECs upon meningitic E. coli infection.

Fu, J., Li, L., Yang, X., Yang, R., Amjad, N., Liu, L., ... & Wang, X. (2019). Transactivated epidermal growth factor receptor recruitment of α-actinin-4 from F-actin contributes to invasion of brain microvascular endothelial cells by meningitic Escherichia coli. Frontiers in cellular and infection microbiology, 8, 448.

Figure 2 Western blotting verification of the EGFR–ACTN4 interaction in response to infection with meningitic E. coli PCN033.

The scale indicates 20 μm.

Fu, J., Li, L., Yang, X., Yang, R., Amjad, N., Liu, L., ... & Wang, X. (2019). Transactivated epidermal growth factor receptor recruitment of α-actinin-4 from F-actin contributes to invasion of brain microvascular endothelial cells by meningitic Escherichia coli. Frontiers in cellular and infection microbiology, 8, 448.

Figure 3 Immune response in Balb/c female mice injected with KLHconjugated antigenic peptides of α-ACTN4 peptides.

Antibody titers in sera of control (n=14) and immunized mice (n=14) were detected by ELISA at different time intervals.

Mande, P. V., Thomas, S., Khan, S., Jadhav, S., & Khole, V. V. (2012). Immunization with ovarian autoantigens leads to reduced fertility in mice following follicular dysfunction. Reproduction, 143(3), 309.

Figure 4 Transverse sections of ovaries (stained with hematoxylin and eosin) of mice showing histological changes following administration of different peptides of group 1 (α-ACTN4).

Panels a1–a4 represent sections of ovaries of control mice immunized with PBS alone showing normal oocyte.

Mande, P. V., Thomas, S., Khan, S., Jadhav, S., & Khole, V. V. (2012). Immunization with ovarian autoantigens leads to reduced fertility in mice following follicular dysfunction. Reproduction, 143(3), 309.