Mouse Anti-ADIPOR1 Recombinant Antibody (clone FY072401)
CAT#: VS-0724-FY9
This is a human monoclonal antibody that binds to human AdipoR1. Human AdipoR1 and AdipoR2 belong to the progesterone and adipoQ receptor families and are receptors for the anti-diabetic adipokine adiponectin. AdipoR1 activates the AMP-activated protein kinase (AMPK) pathway, while AdipoR2 activates the peroxisome proliferator-activated receptor-α (PPAR-α) pathway, leading to increased expression of uncoupling protein 2 (UCP2).
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000159346-ADIPOR1
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Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human AdipoR1
- Species Reactivity
- Human
- Clone
- FY072401
- Applications
- Immunoassay
- Related Disease
- Gestational Diabetes and Anorexia Nervosa
Product Property
- Clonality
- Monoclonal Antibody
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Stabilizer
- No Stabilizers
- Sterility
- 0.2 μM filtered
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Adiponectin Receptor 1; Progestin And AdipoQ Receptor Family Member 1; Progestin And AdipoQ Receptor Family Member I; TESBP1A; PAQR1; Adiponectin Receptor Protein 1; ACDCR1; CGI-45; CGI45
- Gene ID
- 51094
- UniProt ID
- Q96A54
- Long Name
- Adiponectin Receptor 1
- Sequence Similarities
- Belongs to the ADIPOR family.
- Cellular Localization
- Cell membrane; Multi-pass membrane protein
- Post Translation Modifications
- Ubiquitination at Lys86
Modification sites at PhosphoSitePlus
- Protein Refseq
- XP_024303195.1; XP_047277915.1; XP_054192855.1; NP_001277482.1; NP_001277486.1
- Function
- Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism.
Required for normal glucose and fat homeostasis and for maintaining a normal body weight.
ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "ADIPOR1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0085 | Hi-Affi™ Rabbit Anti-ADIPOR1 Recombinant Antibody (clone DS85AB) | WB, IHC, ICC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0034-CN | Rabbit Anti-ADIPOR1 Recombinant Antibody (clone CBACN-012) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-WK1096 | Rabbit Anti-ADIPOR1 Recombinant Antibody (VS3-WK1096) | WB, ICC, IF, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY185 | Anti-ADIPOR1 Immunohistochemistry Kit | IHC |
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