Anti-AEBP1 (clone W24V78) Recombinant Antibody Coupled Liposome (VS-1024-FY80)
CAT#: VS-1024-FY80
Lipid nanoparticles engineered to specifically target anti-AEBP1 antibodies hold significant promise for both the therapeutic intervention and research of gliomas. By delivering these targeted agents, it is possible to inhibit the expression of AEBP1, thereby influencing key cellular processes related to tumor cell proliferation and survival, which may ultimately lead to increased rates of tumor cell death. Furthermore, the silencing of AEBP1 in glioma cells could have profound effects on their growth dynamics, potentially diminishing the aggressiveness of the tumor and improving treatment outcomes for patients affected by this challenging malignancy.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47724/884_G8_1_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9966/962_E1_2_selected.jpg
Normal Tissue
Figure 3 IHC staining of human duodenum
Immunohistochemical staining of human duodenum shows moderate positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/63595/ihc_selected.jpg
Normal Tissue
Figure 4 IHC staining of human placenta
Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in decidual cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/64970/151593_A_3_7_selected.jpg
Normal Tissue
Figure 5 IHC staining of human stomach
Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9966/ihc_selected.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (ASC diff, BJ, BJ hTERT+, fHDF/TERT166, JURKAT, WM-115)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000106624-AEBP1
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More Infomation
Specifications
- Potential Clinical Applications
- Glioma
Product Composition
- Clone
- W24V78
- Antibody Type
- IgG
- Antibody Host
- Mouse
- Antibody Reactivity
- Human
- Antibody Description
- The recombinant mouse antibody exhibits a highly specific binding affinity for human AEBP1, a protein that plays a crucial role in various biological processes. This antibody has been engineered to recognize and bind to the AEBP1 antigen with exceptional precision, ensuring minimal cross-reactivity with other proteins. Such specificity makes it an invaluable tool for research and therapeutic applications aimed at understanding the function of AEBP1 in human health and disease.
Product Property
- Storage
- See in the COA
- Storage Shelf Time
- See in the COA
Target Information
- Target
- AEBP1
- Introduction
- This gene encodes a member of carboxypeptidase A protein family. The encoded protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation. Studies in mice suggest that this gene functions in wound healing and abdominal wall development. Overexpression of this gene is associated with glioblastoma.
- Alternative Names
- AE Binding Protein 1; Aortic Carboxypeptidase-Like Protein 2; AE-Binding Protein 1; ACLP; Adipocyte Enhancer Binding Protein 1
- Full Name
- AE Binding Protein 1
- Gene ID
- 165
- UniProt ID
- Q8IUX7
- Sequence Similarities
- Belongs to the peptidase M14 family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- Phosphorylated by MAPK1 in vitro.
Glycosylation at Asn528, Asn480, and Asn922
Ubiquitination at Lys753
- Protein Refseq
- XP_011513464.1; XP_054213349.1; XP_054213350.1; NP_001120.3
- Function
- As a positive regulator of collagen fibrillogenesis, it is probably involved in the organization and remodeling of the extracellular matrix.
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Datasheet
MSDS
COA
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See other products for "AEBP1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0498MZ | Mouse Anti-AEBP1 Recombinant Antibody (clone CBLS-056) | IHC-P, WB | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0097 | Hi-Affi™ Rabbit Anti-AEBP1 Recombinant Antibody (clone DS97AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC4445 | PE-A*01:01/Human AEBP1 (ETEQPTLDY) MHC Tetramer | FCM | |
| MHC-LC4446 | PE-A*69:01/Human AEBP1 (ETEQPTLDY) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY200 | Anti-AEBP1 Immunohistochemistry Kit | IHC |
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