AbPlus™ Anti-AGT Magnetic Beads (VS-0724-YC582) (CAT#: VS-0724-YC582)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-AGT specific antibody

• Target
• AGT

• Immunogen
• Recombinant human SerpinA8/angiotensinogen, aa 1-485.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008]

• Alternative Names
• Angiotensinogen; Serpin Peptidase Inhibitor, Clade A, Member 8; Alpha-1 Antiproteinase, Antitrypsin; Serpin A8; SERPINA8; Serine (Or Cysteine) Proteinase Inhibitor; Fetal-Liver Predominant Transporter 1;

• Gene ID
• 183

• UniProt ID
• P01019

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