AbPlus™ Anti-AGT Magnetic Beads (VS-0724-YC582)
CAT#: VS-0724-YC582
The AbPlus Anti-AGT Magnetic Beads (VS-0724-YC582) is an innovative affinity resin which is bound with anti-AGT specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of AGT protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human duodenum
Immunohistochemical staining of human duodenum shows distinct positivity in plasma, glandular cells were negative.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25798/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25798/151642_B_8_5.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Hepatocytes Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25798/151642_A_8_4.jpg
Normal Tissue
Figure 4 Kidney
Proximal tubules (cell body) Staining: High Intensity: Strong Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25798/151642_A_8_5.jpg
RNA Expression
Figure 5 RNA cell line category: Group enriched (Hep G2, THP-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000135744-AGT
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-AGT specific antibody
- Target
- AGT
- Immunogen
- Recombinant human SerpinA8/angiotensinogen, aa 1-485.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008]
- Alternative Names
- Angiotensinogen; Serpin Peptidase Inhibitor, Clade A, Member 8; Alpha-1 Antiproteinase, Antitrypsin; Serpin A8; SERPINA8; Serine (Or Cysteine) Proteinase Inhibitor; Fetal-Liver Predominant Transporter 1;
- Gene ID
- 183
- UniProt ID
- P01019
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "AGT"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-008 | Mouse Anti-AGT Recombinant Antibody (clone mAb131) | WB, IF, FuncS | Mouse IgG1, κ |
| MOB-0620MZ | Mouse Anti-AGT Recombinant Antibody (clone CHO/LB/5I) | ELISA | Mouse IgG2a |
| MRO-0097-CN | Rabbit Anti-AGT Recombinant Antibody (clone CBACN-031) | WB, IF, IP | Rabbit IgG |
| ZG-0534J | Rabbit Anti-AGT Recombinant Antibody (clone 8A9) | ELISA, IHC | Rabbit IgG |
| VS3-CJ223 | Rabbit Anti-AGT Recombinant Antibody (VS3-CJ223) | WB, ICC, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-008 | Mouse Anti-AGT Recombinant Antibody (clone mAb131); Fab Fragment | WB, IF, FuncS | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-008 | Mouse Anti-AGT Recombinant Antibody (clone mAb131); scFv Fragment | WB, IF, FuncS | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0103 | Hi-Affi™ Rabbit Anti-AGT Recombinant Antibody (clone DS103AB) | FC, IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY60 | Anti-AGT Immunohistochemistry Kit | IHC | |
| VS-0525-XY226 | Anti-Mouse AGT Immunohistochemistry Kit | IHC | |
| VS-0525-XY225 | Anti-Human AGT Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC435 | Recombinant Anti-AGT Vesicular Antibody, EV Displayed (VS-0425-YC435) | ELISA, FC, Cell-uptake |
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